Compound

D0742 | 4-nitrosophenol

Molecular Formula C6H5NO2
Molecular Weight 123.11
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 4.71±2.31 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 15.85 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]


H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]


P201, P202, P264, P270, P273, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

Aggregated GHS information provided by 75 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H242 (50.67%): Heating may cause a fire [Danger Self-reactive substances and mixtures


Organic peroxides]


H301 (26.67%): Toxic if swallowed [Danger Acute toxicity, oral]


H302 (73.33%): Harmful if swallowed [Warning Acute toxicity, oral]


H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]


H341 (100%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H411 (73.33%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]


H413 (26.67%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P201, P202, P210, P220, P234, P264, P270, P273, P280, P281, P301+P310, P301+P312, P305+P351+P338, P308+P313, P310, P321, P330, P370+P378, P391, P403+P235, P405, P411, P420, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]


H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]


H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]


H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]


P201, P202, P264, P270, P273, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 1,4-Benzoquinone 4-oxime 1,4-Benzoquinone monoxime 1,4-benzoquinone mono-oxime
    104-91-6 2, 4-hydroxyimino- 2,4-dione, monooxime
    2,5-Cyclohexadien-1-one, 4-hydroxyimino- 2,5-Cyclohexadiene-1,4-dione, monooxime 2,5-Cyclohexadiene-1,4-dione, monooxime (9CI)
    4-(hydroxyimino)cyclohexa-2,5-dien-1-one 4-07-00-02073 (Beilstein Handbook Reference) 4-Benzoquinone Monoxime
    4-Hydroxyimino-2,5-cyclohexadiene-1-one 4-NITROSOPHENOL 4-Nitroso-phenol
    4-Nitrosofenol 4-Nitrosofenol [Czech] 4-Nitrosophenol (wetted with ca. 40% Water) (unit weight on dry weight basis);
    4-Nitrosophenol(wettedwithca.40%Water)(unitweightondryweightbasis) 4-hydroxyimino-cyclohexa-2,5-dien-1-one 55EB58H2UP
    637-62-7 A801099 ACMC-1BVF6
    AI3-19026 AKOS006230373 AKOS006311740
    AM86242 BRN 1856695 BRN 2040595
    CAS-104-91-6 CCRIS 4710 CHEMBL104353
    CHEMBL3276923 CTK0H8028 DSSTox_CID_5991
    DSSTox_GSID_25991 DSSTox_RID_77981 DTXSID0025991
    DTXSID0075287 EINECS 203-251-6 FCH917241
    FT-0631578 FT-0662579 HSDB 5362
    InChI=1/C6H5NO2/c8-6-3-1-5(7-9)2-4-6/h1-4,8H JSTCPNFNKICNNO-UHFFFAOYSA- JSTCPNFNKICNNO-UHFFFAOYSA-N
    KS-0000175K LS-383 LS-56330
    N0374 NCGC00249111-01 NCGC00257216-01
    NCGC00259303-01 NSC 239647 NSC 3124
    NSC-239647 NSC-3124 NSC239647
    NSC3124 Nitrosophenol Phenol, 4-nitroso-
    Phenol, p-nitroso- Q27261304 Quinone 4-oxime
    Quinone monooxime Quinone monoxime Quinone oxime
    R326 SC-17657 SCHEMBL107699
    SCHEMBL232995 STL453714 TC-168616
    Tox21_201754 Tox21_303059 UNII-55EB58H2UP
    VZ35554 W-108801 WLN: L6V DYJ DUNQ
    WLN: QR DNO ZINC1669666 ZINC96337078
    ZX-AT008557 benzoquinone monooxime benzoquinone oxime
    mono-nitroso phenol p-Benzoquinone 4-oxime p-Benzoquinone monoxime
    p-Benzoquinone, monooxime p-Benzoquinone, monooxime (8CI) p-Chinonmonoxim
    p-Chinonmonoxim [Czech] p-Nitrosophenol p-Quinone monooxime
    p-Quinone monoxime para-Nitrosophenol

    CAS Number 104-91-6, 637-62-7, 87029-84-3
    PubChem Compound 7729