Compound
D0772 | alpha-amylcinnamyl alcohol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 38.11±17.40 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 56.23 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 4.83±4.07 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
Aggregated GHS information provided by 316 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H315 (87.66%): Causes skin irritation [Warning Skin corrosion/irritation] H317 (87.97%): May cause an allergic skin reaction [Warning Sensitization, Skin] H319 (95.89%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P272, P280, P302+P352, P305+P351+P338, P321, P332+P313, P333+P313, P337+P313, P362, P363, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rabbit | LD50 | skin | > 5gm/kg (5000mg/kg) | Food and Cosmetics Toxicology. Vol. 12, Pg. 817, 1974. | |
| rat | LD50 | oral | 4gm/kg (4000mg/kg) | Food and Cosmetics Toxicology. Vol. 12, Pg. 817, 1974. | |
| (2E)-2-Pentyl-3-phenyl-2-propen-1-ol | (2E)-2-benzylideneheptan-1-ol | (E)-2-Amyl-3-phenyl-2-propene-1-ol |
| (E)-2-benzylideneheptan-1-ol | (E)-alpha-amylcinnamyl alcohol | .alpha.-Amylcinnamic alcohol |
| .alpha.-Amylcinnamyl alcohol | 0494AA | 1-HEPTANOL, 2-BENZYLIDENE- |
| 1-Heptanol, 2-(phenylmethylene)- | 1-Heptanol, 2-(phenylmethylene)-, (E)- | 101-85-9 |
| 184900-07-0 | 2-(Phenylmethylene)-1-heptanol | 2-Amyl-3-phenyl-2-propen-1-ol |
| 2-Benzylidene-1-heptanol | 2-Benzylideneheptanol | 2-Pentyl-3-phenyl-2-propen-1-ol |
| 2-Pentyl-3-phenylprop-2-en-1-ol | 2-Pentyl-3-phenylprop-2-en-1-ol. | 2-Pentylcinnamic alcohol |
| 2-benzylideneheptan-1-ol | 3-06-00-02542 (Beilstein Handbook Reference) | 6240Z8QTPR |
| AI3-28807 | AKOS024319237 | ALPHA-AMYLCINNAMYLALCOHOL |
| BRN 3127316 | Buxinol | EINECS 202-982-8 |
| FEMA No. 2065 | LIPHCKNQPJXUQF-SDNWHVSQSA-N | LS-2560 |
| Q27263433 | SCHEMBL1171617 | ST2416483 |
| UNII-6240Z8QTPR | UNII-DKB52S61GU component LIPHCKNQPJXUQF-SDNWHVSQSA-N | ZINC5192544 |
| a-amylcinnamyl alcohol | alpha-Amylcinnamic alcohol | alpha-Amylcinnamyl alcohol |
| alpha-Amylcinnamyl alcohol, (E)- | alpha-Amylcinnamyl alcohol, United States Pharmacopeia (USP) Reference Standard; | alpha-Amylcinnamyl alcohol, analytical standard |
| alpha-Amylcinnamyl alcohol, mixture with Amyl hydrocinnamyl alcohol | alpha-Pentylcinnamyl alcohol |
| CAS Number | 101-85-9, 1023-94-5, 184900-07-0 |
| PubChem Compound | 5368491 |