D0777 | amsacrine hydrochloride
L
L01XX01 Amsacrine
[L01XX] Other antineoplastic agents
[L01X] OTHER ANTINEOPLASTIC AGENTS
[L01] ANTINEOPLASTIC AGENTS
[L] Antineoplastic and immunomodulating agents
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 10.34±2.45 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 56.23 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 37.65±3.06 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
  |
Danger |
Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (97.44%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| 3442AH | 4'-(9-Acridinylamino)methanesulfon-m-aniside monohydrochloride | 4-(9-Acridinylamino)-N-(methanesulfonyl)-m-anisidine hydrochloride |
| 54301-15-4 | A 9809 | AMSA hydrochloride;m-AMSA hydrochloride;CI-880 hydrochloride;SN-11841 hydrochloride;acridinyl anisidide hydrochloride; |
| AOB4198 | Amsacrine (hydrochloride) | Amsacrine HCl |
| Amsacrine hydrochloride | Amsacrine hydrochloride, >=98% (TLC), powder | C21H19N3O3S.ClH |
| CAS-54301-15-4 | CCG-221458 | CCRIS 9342 |
| CHEMBL1256655 | CS-1943 | DSSTox_CID_17186 |
| DSSTox_GSID_37186 | DSSTox_RID_79305 | DTXSID2037186 |
| EU-0100154 | FT-0658261 | HY-13551A |
| INB0000947 | LP00154 | LS-90297 |
| M-Amsacrine | METHANESULFON-M-ANISIDIDE 4'-(9-ACRIDINYLAMINO)-, | MFCD07799963 |
| MLS002153376 | Methanesulfon-m-anisidide, 4'-(9-acridinylamino)-, monohydrochloride | Methanesulfon-m-anisidine, 4'-((9-acridinyl)amino)-, hydrochloride |
| Methanesulfonamide, N-(4-(9-acridinylamino)-3-methoxyphenyl)-, monohydrochloride | Methanesulfonamide, N-(4-(9-acridinylamino)-3-methoxyphenyl)-, monohydrochloride (9CI) | Methanesulfone-m-anisidine-4'-((9-acridinyl)amino) hydrochloride |
| Methanesulfone-m-anisidine-4'-[(9-acridinyl)amino] hydrochloride | Methanesulfonyl-m-anisidine, 4'-(9-acridinylamino)-, monohydrochloride | Methansulfon-m-aniside, monohydrochloride |
| N-(4-(9-ACRIDINYLAMINO)-3-METHOXYPHENYL)METHANESULFONAMIDE MONOHYDROCHLORIDE | N-(4-(9-Acridinylamino)-3-methoxyphenyl)-methanesulfonamide monohydrochloride | N-(4-(9-Acridinylamino)-3-methoxyphenyl)methanesulfonamidemonohydrochloride |
| N-(4-(Acridin-9-ylamino)-3-methoxyphenyl)methanesulfonamide hydrochloride | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide;hydrochloride | NCGC00093644-01 |
| NCGC00260839-01 | NCI-C03190 | NSC 141549 |
| NSC141549 | Q27290741 | SCHEMBL1320825 |
| SMR000875352 | SR-01000075699 | SR-01000075699-1 |
| Tox21_111212 | Tox21_500154 | U66HX4K4CO |
| UNII-U66HX4K4CO | m-Amsa hydrochloride | s5627 |