D0779 | amylmetacresol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 11.17±0.65 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 8.69 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
    |
Danger |
Aggregated GHS information provided by 46 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H314 (15.22%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H361 (15.22%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H410 (13.04%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P264, P270, P273, P280, P281, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P321, P330, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | oral | 1500mg/kg (1500mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 32, Pg. 592, 1935. | |
| 05W904P57F | 1300-94-3 | 2-Amyl-5-methylphenol |
| 3-06-00-02005 (Beilstein Handbook Reference) | 5-Methyl-2-pentylphenol | 5-methyl-2-N-pentylphenol, AldrichCPR |
| 5-methyl-2-n-pentylphenol | 53043-14-4 | 6-AMYL META CRESOL |
| 6-Amyl-m-cresol | 6-Pentyl-m-cresol | 6-n-Amyl-m-cresol |
| 6-n-Pentyl-m-cresol | 6004AF | AK-57298 |
| AKOS015912095 | AX8104727 | Amilmetacresol |
| Amilmetacresol [Spanish] | Amyl metacresol | Amylmetacresol |
| Amylmetacresol [INN:BAN] | Amylmetacresolum [Latin] | BRN 2440952 |
| CAS-1300-94-3 | CHEBI:48213 | CHEMBL1512677 |
| CTK6D7214 | DB13908 | DS-15450 |
| DSSTox_CID_26791 | DSSTox_GSID_46791 | DSSTox_RID_81908 |
| DTXSID8046791 | EINECS 215-094-0 | FT-0620948 |
| KS-00000F7A | LS-55434 | NCGC00180998-01 |
| OR30625 | Phenol, 5-methyl-2-pentyl- | Phenol, 5-methyl-2-pentyl- (9CI) |
| Q1946346 | SCHEMBL302197 | SR-01000944860 |
| SR-01000944860-1; | ST24044872 | STL453583 |
| Tox21_112651 | UNII-05W904P57F | W-108357 |
| ZINC2039651 | ZX-AT015305 | amylmetacresolum |
| m-Cresol, 6-pentyl- | s6173 |
| DrugBank Name | amylmetacresol |
| DrugBank | DB13908 |
| CAS Number | 1300-94-3, 53043-14-4 |
| PubChem Compound | 14759 |
| ChEBI | 48213 |