D0786 | barban
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 22.54±4.10 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 25.12 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 35.97±7.53 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
  |
Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P261, P264, P270, P272, P273, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
Aggregated GHS information provided by 195 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin] H400 (21.03%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P270, P272, P273, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P261, P264, P270, P272, P273, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] |
P261, P264, P270, P272, P280, P301+P312, P302+P352, P321, P330, P333+P313, P363, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rabbit | LD50 | skin | 23000mg/kg (23000mg/kg) | "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976. | |
| rat | LD50 | oral | 527mg/kg (527mg/kg) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 35, 1982. | |
| rabbit | LD50 | oral | 600mg/kg (600mg/kg) | Pharmacological Reviews. Vol. 14, Pg. 225, 1962. | |
| mammal (species unspecified) | LD50 | unreported | 240mg/kg (240mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 202, 1971. | |
| mouse | LD50 | oral | 322mg/kg (322mg/kg) | Farmakologiya i Toksikologiya Vol. 35, Pg. 356, 1972. | |
| rat | LC50 | inhalation | 27400mg/m3/4H (27400mg/m3) | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 952, 1986. | |
| guinea pig | LD50 | oral | 240mg/kg (240mg/kg) | Pharmacological Reviews. Vol. 14, Pg. 225, 1962. | |
| rat | LD50 | skin | > 1600mg/kg (1600mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. | |
| rat | LD50 | unreported | 527mg/kg (527mg/kg) | Environmental Quality and Safety, Supplement. Vol. 3, Pg. 618, 1975. | |
| (3-Chlorophenyl)carbamic acid 4-chloro-2-butynyl ester | (4-Chloor-but-2-yn-yl)-N-(3-chloor-fenyl)-carbamaat | (4-Chloor-but-2-yn-yl)-N-(3-chloor-fenyl)-carbamaat [Dutch] |
| (4-Chlor-but-2-in-yl)-N-(3-chlor-phenyl)-carbamat | (4-Chlor-but-2-in-yl)-N-(3-chlor-phenyl)-carbamat [German] | (4-Cloro-but-2-in-il)-N-(3-cloro-fenil)-carbammato |
| (4-Cloro-but-2-in-il)-N-(3-cloro-fenil)-carbammato [Italian] | 0361AA | 101-27-9 |
| 101555-42-4; | 2-Butyn-1-ol, 4-chloro-, m-chlorocarbanilate | 2-Butyn-1-ol, m-chlorocarbanilate |
| 2-Butynyl 4-chloro-m-chlorocarbanilate | 2-Butynyl-4-chloro-m-chlorocarbanilate | 3-CHLOROCARBANILIC ACID 4-CHLORO-2-BUTYNYL ESTER |
| 33306K781F | 4-Chloro-2-butynyl 3-chlorocarbanilate | 4-Chloro-2-butynyl 3-chlorophenylcarbamate |
| 4-Chloro-2-butynyl 3-chlorophenylcarbamate # | 4-Chloro-2-butynyl N-(3-chlorophenyl)carbamate | 4-Chloro-2-butynyl m-chlorocarbanilate |
| 4-Chloro-2-butynyl m-chlorophenylcarbamate | 4-Chloro-2-butynyl m-chlorophenylcarbamate (8CI) | 4-Chloro-2-butynyl meta-chlorocarbanilate |
| 4-Chloro-2-butynyl-m-chlorocarbanilate | 4-Chloro-2-butynylm-chlorocarbanilate | 4-Chlorobut-2-ynyl 3-chlorophenylcarbamate |
| 4-Chlorobut-2-ynyl-m-chlorocarbanilate | 4-chlorobut-2-yn-1-yl (3-chlorophenyl)carbamate | 4-chlorobut-2-ynyl N-(3-chlorophenyl)carbamate |
| A 980 | A-980 | A980 |
| AI3-28201 | AKOS015904119 | BARBAN |
| BRN 2376181 | Barbamate | Barban [ANSI:BSI:ISO] |
| Barban, analytical standard | Barbanate | Barbane |
| Barbane [ISO-French] | C-16049 | C-847 |
| C19059 | CAS-101-27-9 | CC-14843 |
| CHEBI:33421 | CHEMBL1570161 | CS-847 |
| CTK6H4434 | Carbamic acid, (3-chlorophenyl)-, 4-chloro-2-butynyl ester | Carbamic acid, (3-chlorophenyl)-, 4-chloro-2-butynyl ester (9CI) |
| Carbamic acid, 4-chloro-2-butynyl ester | Carbanilic acid, 4-chloro-2-butynyl ester | Carbanilic acid, m-chloro-, 4-chloro-2-butynyl ester |
| Carbin | Carbine | Carbyne |
| Carbyne (herbicide) | Caryne | Caswell No. 068 |
| Chlorinat | Chloro-2-butynyl m-chlorocarbamate | DSSTox_CID_21617 |
| DSSTox_GSID_41617 | DSSTox_RID_79788 | DTXSID3041617 |
| EINECS 202-930-4 | EPA Pesticide Chemical Code 017601 | FT-0631535 |
| Fisons B25 | HSDB 1514 | J-000356 |
| Karbin | LS-50978 | MCOQHIWZJUDQIC-UHFFFAOYSA-N |
| N-(3-Chloro phenyl) carbamate de 4-chloro 2 butynyle | N-(3-Chloro phenyl) carbamate de 4-chloro 2 butynyle [French] | N-(3-Chloro phenyl)carbamate de 4-chloro 2-butynyle |
| N-(m-chlorophenyl)carbamic acid,4-chloro-2-butynyl ester | NCGC00166272-01 | NCGC00166272-02 |
| NCGC00254577-01 | NSC 29168 | NSC-29168 |
| NSC29168 | Neoban | Q9165259 |
| RCRA waste no. U280 | S 847 | S-847 |
| S847 | SCHEMBL59626 | Tox21_300669 |
| UNII-33306K781F | WLN: G2UU2OVMR CG | ZINC1652009 |
| m-Chlorocarbanilic acid, 4-chloro-2-butynyl ester |