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Compound

D0822 | buclizine dihydrochloride

Molecular Formula C28H35Cl3N2
Molecular Weight 505.9
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 32.23±2.10 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL human HepG2 MMP assay Negative IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163


  • (rs)-1-(4-t-butylbenzyl)-4-(4-chlorobenzhydryl) piperazine dihydrochloride 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)-(phenyl)methyl)piperazine dihydrochloride
    1-(4-tert-butylbenzyl)-4-[(4-chlorophenyl)(phenyl)methyl]piperazine dihydrochloride 1-(4-tert-butylbenzyl)-4-[(4-chlorophenyl)(phenyl)methyl]piperazinediium dichloride 1-(p-Chlorobenzhydryl)-4-(p-t-butylbenzyl)diethylenediamine dihydrochloride
    1-(p-tert-Butylbenzyl)-4-(p-chloro-alpha-phenylbenzyl)piperazine dihydrochloride 1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]piperazine;dihydrochloride
    1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride 129-74-8 129B748
    163837-35-2 163837-36-3 4CA-0326
    A 7668 AK-54927 AKOS016004771
    ANW-66382 API0001773 AX8118925
    Aphilan R BCP0726000050 BCP22428
    BCP9000459 BUCLIZINE, DIHYDROCHLORIDE Bucladin
    Bucladin S Bucladin-S Buclina
    Buclizine HCl Buclizine dihydrochloride Buclizine dihydrochloride, >=98% (HPLC)
    Buclizine hydrochloride Buclizine hydrochloride (USAN) Buclizine hydrochloride [USAN]
    Buclizine hydrochloride, (+)- Buclizine hydrochloride, (-)- C28H33ClN2
    C28H33ClN2.2HCl CAS-129-74-8 CHEBI:61193
    CHEMBL2360580 CTK8C1377 D02089
    DSSTox_CID_25091 DSSTox_GSID_45091 DSSTox_RID_80665
    DTXSID5045091 EINECS 204-962-4 EOP5593FPH
    FT-0663892 Histabutyzine dihydrochloride Histabutyzine hydrochloride
    J-005711 KS-00000FU4 KS-1250
    LS-110573 Longifene NCGC00013315-01
    NSC 25141 Perlapine, >=98% (HPLC) Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)methyl)-, dihydrochloride
    Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)methyl)-, dihydrochloride, (+)- Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)methyl)-, dihydrochloride, (-)- Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)methyl)-, hydrochloride (1:2);
    Piperazine, 1-(p-tert-butylbenzyl)-4-(p-chloro-alpha-phenylbenzyl)-, dihydrochloride Postafeno Q27130875
    Q710 SCHEMBL123751 ST24037299
    Softran TC-155127 Tox21_110023
    UCB 4445 UCB-4445 UNII-EOP5593FPH
    UNII-V4OCE982YU V4OCE982YU Vibazine (TN)
    Vibazine hydrochloride buclizine 2HCl buclizine-hcl
    s4140

    CAS Number 129-74-8, 163837-35-2, 163837-36-3, 82-95-1
    PubChem Compound 65463
    ChEBI 61193