Drug

D0847 | chrysin

Molecular Formula C15H10O4
Molecular Weight 254.24
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 5.05±2.76 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 7.08 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 30.60±28.39 rat hepatocytes MMP assay decrease IC50 163

Organism Test type Route Dose (normalized dose) Effect Source
rat LD50 subcutaneous 500mg/kg (500mg/kg) Zeitschrift fuer Krebsforschung. Vol. 74, Pg. 241, 1970.
mouse LD50 intraperitoneal 1gm/kg (1000mg/kg) JNCI, Journal of the National Cancer Institute. Vol. 62, Pg. 911, 1979.


  • 34B3B4AD-EEDD-4943-A1C6-8857D2FAA8E0 3CN01F5ZJ5 3ebo
    480-40-0 4H-1,3-BENZODIOXIN-8-CARBONYL CHLORIDE,6-FLUORO-,M 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-phenyl-
    4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-phenyl- (9CI) 4H-1-Benzopyran-4-one,7-dihydroxy-2-phenyl- 4des
    5, 7-Dihydroxyflavone 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one, 9CI
    5,7-Dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one #
    5,7-Dihydroxy-2-phenyl-chromen-4-one 5,7-Dihydroxyflavone 5,7-bis(oxidanyl)-2-phenyl-chromen-4-one
    5,7-diOH-Flavone 5,7-dihydroxy-2-phenyl-1-benzopyran-4-one 5,7-dihydroxy-2-phenyl-4H-benzo[b]pyran-4-one
    5,7-dihydroxy-2-phenylchromen-4-one 5-18-04-00076 (Beilstein Handbook Reference) 57D
    773134-15-9; 80C400 A-8723
    A827426 AB0006577 AB00513947
    AB1003937 AC-10052 ACon1_000087
    AKOS000275936 ALBB-015581 ANW-43827
    BBL010449 BCP22863 BCP9000172
    BDBM7461 BIDD:ER0484 BPBio1_000746
    BRD-K22861715-001-07-5 BRD-K22861715-001-12-5 BRN 0233276
    BSPBio_000678 BSPBio_002514 BSPBio_003018
    C10028 C1652 CAS-480-40-0
    CC-079 CCG-40148 CHEBI:75095
    CHEMBL117 CS-7531 CTK4J0553
    Chrysin, 97% Chrysin, 99+% Chrysin, analytical standard
    Chrysin,(S) Chrysine Chrysinic acid
    Crysin DB15581 DSSTox_CID_2396
    DSSTox_GSID_22396 DSSTox_RID_76571 DTXSID1022396
    DivK1c_000614 EINECS 207-549-7 FLAVONE, 5,7-DIHYDROXY-
    FT-0082809 FT-0619846 FT-0686390
    Flavone,7-dihydroxy- GS-0927 GTPL8789
    HMS1570B20 HMS1921E20 HMS2097B20
    HMS2268I23 HMS3468N08 HMS3655L20
    HMS501O16 HY-14589 IDI1_000614
    KBio1_000614 KBio2_000725 KBio2_003293
    KBio2_005861 KBio3_002238 KBioGR_001200
    KBioSS_000725 KS-00000HC3 LMPK12110189
    LS-68972 MCULE-7719714939 MEGxp0_001416
    MFCD00006834 MLS000697728 MLS001074879
    MLS006011841 N1336 NCGC00016456-01
    NCGC00016456-02 NCGC00016456-03 NCGC00016456-04
    NCGC00016456-05 NCGC00016456-06 NCGC00016456-07
    NCGC00016456-08 NCGC00016456-09 NCGC00016456-10
    NCGC00016456-12 NCGC00094842-01 NCGC00094842-02
    NCGC00094842-03 NCGC00094842-04 NCGC00094842-05
    NCGC00168807-01 NCGC00168807-02 NCGC00168807-03
    NCGC00168807-04 NCGC00255307-01 NCI60_003886
    NINDS_000614 NSC 407436 NSC-407436
    NSC407436 Ois 3 Oprea1_045160
    Prestwick0_000889 Prestwick1_000889 Prestwick2_000889
    Prestwick3_000889 PubChem9839 Q973741
    RTIXKCRFFJGDFG-UHFFFAOYSA-N RTR-017608 S00112
    SBB012459 SC-04753 SC-57642
    SCHEMBL44474 SDCCGMLS-0066586.P001 SMP1_000070
    SMR000112318 SPBio_000766 SPBio_002897
    SPECTRUM1500709 SPECTRUM1505144 SR-01000765660
    SR-01000765660-3 SR-01000765660-4 ST069324
    STK801609 SW197197-2 Spectrum2_000753
    Spectrum3_001399 Spectrum4_000780 Spectrum5_001503
    Spectrum_000245 TR-017608 Tox21_302335
    UNII-3CN01F5ZJ5 ZINC3872070 chrysin
    cid_5281607 s2281

    DrugBank Name chrysin
    DrugBank DB15581
    CAS Number 480-40-0, 773134-15-9, 80-40-0
    PubChem Compound 5281607
    KEGG Compound ID C10028
    ChEBI 75095