Drug

D0850 | cinalukast

Molecular Formula C23H28N2O3S
Molecular Weight 412.5
Structure
State solid

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 28.81±1.17 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 17.34 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 13.54±5.36 rat hepatocytes MMP assay decrease IC50 163


  • (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid (E)-4-[[3-[2-(4-cyclobutyl-2-thiazolyl)-ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid 128312-51-6
    3'-((E)-2-(4-Cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid 3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid 4-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}amino)-2,2-diethyl-4-oxobutanoic acid
    4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid 5E1O433QAI AKOS024456917
    B6930 BDBM50064086 BRD-K72816382-001-01-3
    BZMKNPGKXJAIDV-VAWYXSNFSA-N Butanoic acid, 4-((3-(2-(4-cyclobutyl-2-thiazolyl)ethenyl)phenyl)amino)-2,2-diethyl-4-oxo-, (E)- Butanoic acid, 4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-
    CAS-128312-51-6 CHEBI:126598 CHEBI:93279
    CHEMBL283754 Cinalukast Cinalukast (USAN/INN)
    Cinalukast [USAN:INN] Cinalukast, ~98% (HPLC) D02846
    DB00587 DSSTox_CID_25742 DSSTox_GSID_45742
    DSSTox_RID_81087 DTXSID1045742 HMS3413E03
    HMS3677E03 J-005592 L000942
    MFCD00864778 MLS003899216 N-{3-[(E)-2-(4-Cyclobutyl-thiazol-2-yl)-vinyl]-phenyl}-2,2-diethyl-succinamic acid
    N-{3-[2-(4-Cyclobutyl-thiazol-2-yl)-vinyl]-phenyl}-2,2-diethyl-succinamic acid(Ro 24-5913); NCGC00092300-01 NCGC00092300-02
    Q20817064 RT-012024 Ro 24-5913
    Ro-24-5913 Ro-245913 SCHEMBL37964
    SCHEMBL37965 SMR002543511 Tox21_111191
    Tox21_111191_1 UNII-5E1O433QAI ZINC3803377

    DrugBank Name cinalukast
    DrugBank DB00587
    CAS Number 128312-51-6
    PubChem Compound 6436135
    KEGG Drug D02846
    ChEBI 126598