Drug
D0854 | clofoctol
J
J01XX03 Clofoctol
[J01XX] Other antibacterials
[J01X] OTHER ANTIBACTERIALS
[J01] ANTIBACTERIALS FOR SYSTEMIC USE
[J] Antiinfectives for systemic use
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 1.64±0.13 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 4.35 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 15.67±6.04 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
|
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. H413 (100%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] |
P273, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | ||
| .alpha.-(2,4-Dichlorophenyl)-4-(1,1,3,3-tetramethylbutyl)-o-cresol | 2-((2,4-Dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)phenol | 2-(2,4-Dichlorobenzyl)-4-(1,1,3,3-tetramethylbutyl)phenol |
| 2-(2,4-Dichlorobenzyl)-4-(1,1,3,3-tetramethylbutyl)phenol # | 2-(2,4-dichlorobenzyl)-4-(2,4,4-trimethylpentan-2-yl)phenol | 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)phenol |
| 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol | 2-[2,4-Dichlorobenzyl]-4-[1,1,3,3-tetramethylbutyl]phenol | 2329AH |
| 37693-01-9 | 704083NI0R | AB00052326_04 |
| AB00052326_05 | ACM37693019 | AKOS024374914 |
| BRD-K02900412-001-04-8 | BRD-K02900412-001-05-5 | BRD-K02900412-001-07-1 |
| BRN 2478182 | BSPBio_003070 | C-56242 |
| C21H26Cl2O | CAS-37693-01-9 | CCG-39311 |
| CHEBI:108581 | CHEMBL1476605 | CS-4755 |
| CTK6G7999 | Clofoctol (INN) | Clofoctol [INN] |
| Clofoctol, analytical standard | Clofoctolum | Clofoctolum [INN-Latin] |
| D07244 | DB13237 | DSSTox_CID_25889 |
| DSSTox_GSID_45889 | DSSTox_RID_81203 | DTXSID5045889 |
| DivK1c_000426 | EINECS 253-632-6 | FT-0704662 |
| Gramplus | HMS1922I09 | HMS501F08 |
| HQVZOORKDNCGCK-UHFFFAOYSA-N | HY-B1150 | IDI1_000426 |
| KBio1_000426 | KBio2_002013 | KBio2_004581 |
| KBio2_007149 | KBio3_002570 | KBioGR_000641 |
| KBioSS_002013 | LS-104344 | MCULE-3939000404 |
| MLS002207309 | NCGC00095016-01 | NCGC00095016-02 |
| NCGC00095016-03 | NCGC00095016-05 | NINDS_000426 |
| NSC-758389 | NSC758389 | Octofene |
| Octofene (TN) | Octophene(2,4-dichlorobenzyl)-2(1,1,3,3-tetramethyl-butyl)- 4-phenol; | Pharmakon1600-01503206 |
| Phenol, 2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)- | Phenol, 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)- | Q3680895 |
| SBI-0051786.P002 | SCHEMBL147809 | SMR001306814 |
| SPBio_001346 | SPECTRUM1503206 | SR-01000872766 |
| SR-01000872766-1 | ST51014944 | SW220062-1 |
| Spectrum2_001533 | Spectrum3_001565 | Spectrum4_000161 |
| Spectrum5_001082 | Spectrum_001533 | Tox21_111389 |
| Tox21_111389_1 | UNII-704083NI0R | ZINC2149829 |
| alpha-(2,4-Dichlorophenyl)-4-(1,1,3,3-tetramethylbutyl)-o-cresol | clofoctol |