Compound
D0866 | darbufelone mesylate
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 11.74±2.02 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 5.62 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 7.15±5.41 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| (Z)-2-Amino-5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-4(5H)-thiazolone monomethanesulfonate (salt) | 139340-56-0 | 340D560 |
| 5-((3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-2-imino-4-thiazolidinone methanesulfonate | 5-((Z)-3,5-Di-tert-butyl-4-hydroxybenzylidene)-2-imino-4-thiazolidinone monomethanesulfonate (salt) | 5I2Y40C5PX |
| BCP23976 | CAS-139340-56-0 | CHEMBL109745 |
| CI 1004 | CI-1004 | CI-1004 mesylate |
| D03652 | DSSTox_CID_27246 | DSSTox_GSID_47246 |
| DSSTox_RID_82207 | Darbufelone mesylate | Darbufelone mesylate (USAN) |
| LS-186107 | NCGC00254170-01 | PD-136095-0073; |
| SCHEMBL2683037 | Tox21_300202 | UNII-5I2Y40C5PX |