Drug

D0867 | deltamethrin

Molecular Formula C22H19Br2NO3
Molecular Weight 505.2
Structure

P

P03BA03 Decamethrin


[P03BA] Pyrethrines


[P03B] INSECTICIDES AND REPELLENTS


[P03] ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS


[P] Antiparasitic products, insecticides and repellents


Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 45.88±17.92 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 50.12 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 39.83±14.21 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H331: Toxic if inhaled [Danger Acute toxicity, inhalation]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P261, P264, P270, P271, P273, P301+P310, P304+P340, P311, P321, P330, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

Aggregated GHS information provided by 369 companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


Reported as not meeting GHS hazard criteria by 1 of 369 companies. For more detailed information, please visit ECHA C&L website


Of the 11 notification(s) provided by 368 of 369 companies with hazard statement code(s):


H301 (98.91%): Toxic if swallowed [Danger Acute toxicity, oral]


H331 (100%): Toxic if inhaled [Danger Acute toxicity, inhalation]


H400 (99.46%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P264, P270, P271, P273, P301+P310, P304+P340, P311, P321, P330, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]


H331: Toxic if inhaled [Danger Acute toxicity, inhalation]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P261, P264, P270, P271, P273, P301+P310, P304+P340, P311, P321, P330, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Organism Test type Route Dose (normalized dose) Effect Source
rat LD50 oral 80mg/kg (80mg/kg) Nature. Vol. 248, Pg. 711, 1974.
mouse LDLo intravenous 6mg/kg (6mg/kg) Archives of Toxicology. Vol. 45, Pg. 325, 1980.


  • (1R,3R)-((S)-cyano(3-phenoxyphenyl)methyl) 3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate (1R,3R)-3-(2,2-Dibromovinyl)-2,2-dimethylcyclopropanecarboxylic Acid (S)-alpha-Cyano-3-phenoxybenzyl Ester (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethyl-1-cyclopropanecarboxylic acid [(S)-cyano-(3-phenoxyphenyl)methyl] ester
    (1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylic acid, (S)-alpha-cy ano-3-phenoxybenzyl ester (1R-(1alpha(S*),3alpha))-3-(2,2-dibromoethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl)methyl cyclopropanecarboxylate (1R-(1alpha(S*),3alpha))-Cyano(3-phenoxyphenyl)methyl 3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylate
    (S)-I+/--cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate (S)-alpha-Cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate (S)-alpha-Cyano-3-phenoxybenzyl (1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethyl-cyclopropan-1-carboxylate
    (S)-alpha-Cyano-3-phenoxybenzyl (1R,3S)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate (S)-alpha-Cyano-3-phenoxybenzyl-(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethyl-cyclopropane carboxyate (S)-cyano(3-phenoxyphenyl)methyl (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropane-1-carboxylate
    (S)-cyano(3-phenoxyphenyl)methyl (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylate (S)-cyano[3-(phenyloxy)phenyl]methyl (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylate (s)-alpha-cyano-3-phenoxybenzyl (1r,3r)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate
    .alpha.-cyano-3-phenoxybenzyl [1R-[1.alpha.(S*),3.alpha.]]-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate 2JTS8R821G 3-(2,2-Dibromoethenyl)-2,2-dimethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)methyl ester
    3-(2,2-Dibromoethenyl)-2,2-dimethylcyclopropanecarboxylic acid, cyano(3-phenoxy-phenyl)-, methyl ester 529-EP2274983A1 529-EP2275422A1
    529-EP2280009A1 529-EP2292608A1 529-EP2298076A1
    529-EP2298077A1 529-EP2301353A1 529-EP2305031A1
    529-EP2305034A1 529-EP2305035A1 529-EP2305662A1
    529-EP2308857A1 529-EP2308858A1 529-EP2311816A1
    529-EP2311817A1 529-EP2314583A1 52918-63-5
    918M635 A829307 AI3-29279
    AKOS015895185 API0002244 Butoss
    Butox C10985 CAS-52918-63-5
    CCRIS 3704 CHEBI:4388 CHEMBL1593566
    CTK8F9016 Cislin Crackdown
    Cyano-m-phenoxybenzyl (1R,3R)-3-(2,2-dibromovi nyl)-2,2-dimethylcyclopropanecarboxylate Cyclopropanecarboxylic acid, 3-(2,2-dibromoethenyl)-2,2-dimethyl-, (S)-cyano(3-phenoxyphenyl)methyl ester, (1R,3R)- Cyclopropanecarboxylic acid, 3-(2,2-dibromoethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl)methyl ester, (1R-(1-alpha(S*),3-alpha))-
    Cyclopropanecarboxylic acid, 3-(2,2-dibromoethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl)methyl ester, (1R-(1alpha(s*),3alpha))- Cyclopropanecarboxylic acid, 3-(2,2-dibromoethenyl)-2,2-dimethyl-,(S)-cyano(3-phenoxyphenyl)methyl ester, (1R,3R)- D07785
    D4775 DB13600 DSSTox_CID_381
    DSSTox_GSID_20381 DSSTox_RID_75555 DTXSID8020381
    Decamethrin Decamethrine Decis
    Decis 0.5ULV Decis 1.5ULV Decis 2.5ULV
    Dekametrin Dekametrin (Hungarian) Delta-methrin
    DeltaGard Deltacide Deltagran
    Deltamet hrin Deltamethrin (BAN) Deltamethrin 10 microg/mL in Cyclohexane
    Deltamethrin 100 microg/mL in Cyclohexane Deltamethrin Formulations Deltamethrin [BAN]
    Deltamethrin [BSI:ISO] Deltamethrin solution, 100 ng/muL in cyclohexane, PESTANAL(R), analytical standard Deltamethrin, >=98%
    Deltamethrin, PESTANAL(R), analytical standard Deltamethrin, analytical standard Deltamethrin, certified reference material, TraceCERT(R)
    Deltamethrine Deltamethrine [ISO-French] Deltametryna
    Deltametryna [Polish] EINECS 258-256-6 EPA Pesticide Chemical Code 978051
    Esbecythrin FMC 45498 Glossinex 200
    HSDB 6604 IPO 8831 InChI=1/C22H19Br2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17-,18+,20-/m0/s1;
    K-Obiol K-Othrin K-Othrine
    KS-5078 LS-7298 NCGC00163904-01
    NCGC00163904-02 NCGC00163904-03 NCGC00256465-01
    NCGC00258983-01 New Musigie Nrdc 161
    OMS 1988 OWZREIFADZCYQD-NSHGMRRFSA- Othrin
    Phagase 1 Q422257 RU 22974
    RUP 987 SCHEMBL22196 Scalibor [veterinary] (TN)
    Stricker Striker Suspend
    Tox21_201432 Tox21_303009 UNII-2JTS8R821G
    ZINC1532094 Zodiac Zorcis
    [(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropane-1-carboxylate [(S)-cyano-(3-phenoxyphenyl)methyl] (1R,3R)-3-[2,2-bis(bromanyl)ethenyl]-2,2-dimethyl-cyclopropane-1-carboxylate [(S)-cyano-[3-(phenoxy)phenyl]methyl] (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethy
    alpha-Cyano-3-phenoxybenzyl (1R-(1alpha(S*),3alpha))-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate deltamethrin

    DrugBank Name deltamethrin
    DrugBank DB13600
    CAS Number 52820-00-5, 52918-63-5, 62229-77-0
    PubChem Compound 40585
    KEGG Compound ID C10985
    KEGG Drug D07785
    ChEBI 4388