Compound
D0900 | dodecyl gallate
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| TRANSMEMBRANE POTENTIAL | 2.13 ± 0.2 μM | 72hr | Epimastigote forms of Trypanosoma cruzi of Y strain, | measured by flow cytometry using JC-1 dye (BD MitoScreen kit) | decrease | IC50 | 305 | |
| MEMBRANE POTENTIAL | 4.75±1.81 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 7.94 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 48.72±8.30 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Warning |
H317: May cause an allergic skin reaction [Warning Sensitization, Skin] |
P261, P272, P280, P302+P352, P321, P333+P313, P363, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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Warning |
Aggregated GHS information provided by 51 companies from 3 notifications to the ECHA C&L Inventory. H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P272, P280, P302+P352, P321, P333+P313, P363, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H317: May cause an allergic skin reaction [Warning Sensitization, Skin] |
P261, P272, P280, P302+P352, P321, P333+P313, P363, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | intraperitoneal | 100mg/kg (100mg/kg) | FAO Nutrition Meetings Report Series. Vol. 38A, Pg. 22, 1965. | |
| pig | LD50 | oral | > 6gm/kg (6000mg/kg) | kidney, ureter, and bladder: other changes | Voeding. Vol. 16, Pg. 683, 1955. |
| rat | LD50 | oral | 5gm/kg (5000mg/kg) | kidney, ureter, and bladder: other changes | Voeding. Vol. 16, Pg. 683, 1955. |
| 1166-52-5 | 149030-04-6; | 3,4,5-TRIHYDROXYBENZOIC ACID DODECYL ESTER |
| 3,4,5-Trihydroxy-benzoic acid dodecyl ester | 3,4,5-Trihydroxybenzoic acid, dodecyl ester | 4-10-00-02006 (Beilstein Handbook Reference) |
| 45612DY463 | A803659 | ACMC-1BX1I |
| AK116033 | AKOS001482340 | ANW-16986 |
| AX8126776 | BCP15874 | BDBM50093887 |
| BENZOIC ACID, 3,4,5-TRIHYDROXY-, DODECYL ESTER | BIDD:ER0314 | BRN 2701981 |
| Benzoic acid,4,5-trihydroxy-, dodecyl ester | C-34488 | CAS-1166-52-5 |
| CC-27349 | CCRIS 5568 | CHEMBL16121 |
| CTK3J2874 | DB-108599 | DSSTox_CID_28164 |
| DSSTox_GSID_48189 | DSSTox_RID_82725 | DTXSID0048189 |
| Dodecyl 3,4,5-trihydroxybenzoate | Dodecyl gallate | Dodecyl gallate, European Pharmacopoeia (EP) Reference Standard |
| Dodecyl-3,4,5-trihydroxybenzoate | Dodecylester kyseliny gallove | Dodecylester kyseliny gallove [Czech] |
| E 312 antioxidant | E-312 antioxidant | E312 |
| EINECS 214-620-6 | FT-0626593 | G0015 |
| GALLIC ACID LAURYL ESTER | GS-3008 | Gallic Acid Dodecyl Ester |
| Gallic acid n-dodecyl ester | Gallic acid, dodecyl ester | Gallic acid, dodecyl ester (8CI) |
| Gallic acid, lauryl ester | Gallic acid, n-dodecyl ester | Gallic acid-dodecyl ester |
| J10236 | KS-00000X9I | KSC492Q7J |
| LS-38402 | Lauryl 3,4,5-trihydroxybenzoate | Lauryl 3,5-trihydroxybenzoate |
| Lauryl Gallate(Dodecyl Gallate) | Lauryl gallate | Lauryl gallate, analytical reference material |
| Lauryl gallate, antioxidant, >=99.0% (HPLC) | MCULE-2416501697 | MFCD00002195 |
| NCGC00257297-01 | NCGC00260272-01 | NSC 133463 |
| NSC-133463 | NSC133463 | Nipagallin LA |
| Progallin LA | Q418209 | RPWFJAMTCNSJKK-UHFFFAOYSA-N |
| RT-001095 | SCHEMBL36820 | ST24030406 |
| ST50826966 | SY048252 | Tox21_202724 |
| Tox21_303487 | UNII-45612DY463 | W-108577 |
| WLN: QR BQ CQ EVO12 | ZINC33861415 | antioxidant E 312 |
| antioxidant E-312 | dodecyl 3,4,5-tris(oxidanyl)benzoate | dodecylgallat |
| dodecylgallate | n-Dodecyl 3,4,5-trihydroxybenzoate | n-Dodecyl gallate |
| n-dodecylgallate | s6229 |
| CAS Number | 1166-52-5, 149030-04-6, 3107-33-3 |
| PubChem Compound | 14425 |