Compound
D0901 | dodecylparaben
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 4.19±1.07 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 7.94 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] |
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | subcutaneous | 4900mg/kg (4900mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 128, Pg. 135, 1960. | |
| 2664-60-0 | 4-Hydroxybenzoic Acid Lauryl Ester | 4-Hydroxybenzoic acid dodecyl ester |
| ACM2664600 | ACMC-1CJL7 | AK135794 |
| AKOS016846133 | ANW-26031 | AX8144054 |
| BAYSQTBAJQRACX-UHFFFAOYSA-N | BENZOIC ACID, p-HYDROXY-, DODECYL ESTER | BRN 2739355 |
| Benzoic acid, 4-hydroxy-, dodecyl ester | Benzoic acid, 4-hydroxy-, dodecyl ester (9CI) | C-52774; |
| CAS-2664-60-0 | CHEMBL486647 | CTK3J2619 |
| DSSTox_CID_27859 | DSSTox_GSID_47883 | DSSTox_RID_82612 |
| DTXSID9047883 | Dodecyl 4-hydroxybenzoate | Dodecyl p-hydroxybenzoate |
| Dodecylparaben | EINECS 220-195-8 | FT-0767023 |
| KS-00000ZZ2 | KSC492M1T | LS-37565 |
| Lauryl 4-Hydroxybenzoate | Laurylparaben | MCULE-7140219990 |
| NCGC00248692-01 | NCGC00258100-01 | NSC 309822 |
| NSC-309822 | NSC309822 | RT-000834 |
| SCHEMBL1263037 | ST50826969 | Tox21_200546 |
| ZINC49877946 | dodecyl-4-hydroxybenzoate | n-Dodecyl 4-hydroxybenzoate |
| p-Hydroxybenzoic acid dodecyl ester | p-Oxybenzoesaureduodecylester | p-Oxybenzoesaureduodecylester [German] |
| CAS Number | 2664-60-0 |
| PubChem Compound | 17569 |