Drug
D0906 | emodin
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 1.33±0.78 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 2.51 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 6.28±4.57 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
Aggregated GHS information provided by 51 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H315 (94.12%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (94.12%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (92.16%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| (RS)-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione | 1,3, 8-Trihydroxy-6-methyl-9,10-anthraquinone | 1,3,8-TRIHYDROXY-6-METHYL-9-10-ANTHRACENEDIONE |
| 1,3,8-Tihydroxy-6-methyl-9,10-anthraquinone | 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione | 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione, 9CI |
| 1,3,8-Trihydroxy-6-methyl-9,10-anthraquinone | 1,3,8-Trihydroxy-6-methyl-anthraquinone | 1,3,8-Trihydroxy-6-methylanthra-9,10-quinone |
| 1,3,8-Trihydroxy-6-methylanthra-9,10-quinone # | 1,3,8-Trihydroxy-6-methylanthraquinone | 1,3,8-tri-hydroxy-6-methyl-anthra-quinone |
| 1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9,10-dione | 1,3,8-trihydroxy-6-methyl-anthracene-9,10-dione | 1,3,8-trihydroxy-6-methylanthracene-9,10-dione |
| 1,6,8-trihydroxy-3-methylanthracene-9,10-dione | 1,8-Trihydroxy-6-methyl-9,10-anthraquinone | 1,8-Trihydroxy-6-methylanthraquinone |
| 120667-83-6; | 132796-52-2 | 1f0q |
| 3-Methyl-1,6,8-trihydroxyanthraquinone | 3-Methyl-1,8-trihydroxyanthraquinone | 3-methyl-1,6,8-tris(oxidanyl)anthracene-9,10-dione |
| 3bqc | 3ed0 | 4,5,7-Trihydroxy-2-methylanthraquinone |
| 4,7-Trihydroxy-2-methylanthraquinone | 518-82-1 | 518E821 |
| 6-Methyl-1,3,8-trihydroxy-9,10-anthracenedione | 6-Methyl-1,3,8-trihydroxyanthraquinone | 6-Methyl-1,3,8-trihydroxyanthraquinone |
| 6-methyl-1,3,8-tri-hydroxy-anthra-quinone | 9, 1,3,8-trihydroxy-6-methyl- | 9,10-Anthracenedione, 1,3,8-trihydroxy-6-methyl- |
| 9,10-Anthracenedione, 1,3,8-trihydroxy-6-methyl- (9CI) | A-2578 | A828825 |
| AB0015178 | AB1010271 | AC-1004 |
| ACM132796522 | ACT03256 | ACon1_001939 |
| AI3-38286 | AK160242 | AKOS003348641 |
| AX8006309 | Anthraquinone, 1,3,8-trihydroxy-6-methyl- | Anthraquinone, 1,3,8-trihydroxy-6-methyl- (8CI) |
| Anthraquinone, 6-methyl-1,3,8-trihydroxy- | Anthraquinone,3,8-trihydroxy-6-methyl- | Archin |
| BCP18372 | BDBM11318 | BRD-K58685305-001-03-0 |
| BRN 1888141 | BS0075 | BSPBio_002324 |
| C.I. 75440 | C.I. Natural Yellow 14 | C10343 |
| CAS-518-82-1 | CCG-35263 | CCRIS 3528 |
| CE-131 | CE0035 | CHEBI:42223 |
| CHEMBL289277 | CS-1412 | CTK5B1649 |
| DB07715 | DSSTox_CID_5231 | DSSTox_GSID_25231 |
| DSSTox_RID_77709 | DTXSID5025231 | DivK1c_006428 |
| E 7881 | E0500 | EINECS 208-258-8 |
| EMO | EU-0100552 | Embodin |
| Emdoin | Emodin | Emodin, 95%, tech. |
| Emodin, United States Pharmacopeia (USP) Reference Standard | Emodin, analytical standard | Emodin, from Frangula bark, >=90% (HPLC) |
| Emodin,(S) | Emodin-d4 | Emodol |
| FT-0606539 | Frangula emodin | Frangula-emodin |
| Frangulic acid | Frangulinic acid | GP5697 |
| HMS2230K22 | HMS3261P05 | HMS3373B16 |
| HMS3655H22 | HSDB 7093 | HY-14393 |
| J10081 | K00056 | KA46RNI6HN |
| KBio1_001372 | KBio2_002500 | KBio2_005068 |
| KBio2_007636 | KBio3_001544 | KBioGR_002234 |
| KBioSS_002508 | KS-00000MGZ | KS-5189 |
| LMPK13040008 | LP00552 | LS-3 |
| Lopac-E-7881 | Lopac0_000552 | M371 |
| MCULE-1083063386 | MEGxp0_000460 | MFCD00001207 |
| MLS000563068 | MLS001066370 | MLS004257392 |
| MLS006011712 | N1854 | NCGC00015420-01 |
| NCGC00015420-02 | NCGC00015420-03 | NCGC00015420-04 |
| NCGC00015420-05 | NCGC00015420-06 | NCGC00015420-07 |
| NCGC00015420-08 | NCGC00015420-09 | NCGC00091540-01 |
| NCGC00091540-02 | NCGC00091540-03 | NCGC00091540-04 |
| NCGC00091540-05 | NCGC00257090-01 | NCGC00260544-01 |
| NCGC00261237-01 | NCI60_003906 | NCIMech_000049 |
| NSC 408120 | NSC 622947 | NSC-408120 |
| NSC-622947 | NSC408120 | NSC622947 |
| Persian Berry Lake | Q-100581 | Q4348178 |
| RHMXXJGYXNZAPX-UHFFFAOYSA-N | Rheum emodin | Rheum-emodin |
| SBB066133 | SC-19533 | SCHEMBL177689 |
| SMP2_000211 | SMR000326798 | SPBio_000710 |
| SR-01000075615 | SR-01000075615-1 | SR-01000075615-6 |
| ST055355 | ST24046678 | SW219906-1 |
| Schuttgelb | SpecPlus_000332 | Spectrum2_000895 |
| Spectrum3_000742 | Spectrum4_001757 | Spectrum5_000614 |
| Spectrum_001954 | TNP00318 | TR-018464 |
| Tox21_202999 | Tox21_303218 | Tox21_500552 |
| UNII-KA46RNI6HN | ZINC3824868 | emodin |
| persian b erry lake | rheum emodium | s2295 |