D0925 | fenarimol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 42.59±21.91 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 35.48 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 33.55±2.73 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
  |
Warning |
H361fd: Suspected of damaging fertility Suspected of damaging the unborn child [Warning Reproductive toxicity] H362: May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation] H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P263, P264, P270, P273, P281, P308+P313, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
Aggregated GHS information provided by 328 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H361 (99.09%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H362 (94.82%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation] H411 (100%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P263, P264, P270, P273, P281, P308+P313, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H361fd: Suspected of damaging fertility Suspected of damaging the unborn child [Warning Reproductive toxicity] H362: May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation] H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P263, P264, P270, P273, P281, P308+P313, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Warning |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H320: Causes eye irritation [Warning Serious eye damage/eye irritation] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P264, P270, P281, P301+P312, P305+P351+P338, P308+P313, P309+P311, P314, P330, P337+P313, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | oral | > 200mg/kg (200mg/kg) | Pesticide Manual. Vol. 9, Pg. 362, 1991. | |
| rat | LD50 | oral | 2500mg/kg (2500mg/kg) | Defense des Vegetaux. Vol. 34, Pg. 17, 1980. | |
| bird - wild | LD50 | oral | > 200mg/kg (200mg/kg) | Pesticide Manual. Vol. 9, Pg. 362, 1991. | |
| rabbit | LD50 | skin | > 2gm/kg (2000mg/kg) | Pesticide Manual. Vol. 9, Pg. 362, 1991. | |
| mouse | LD50 | oral | 4500mg/kg (4500mg/kg) | Defense des Vegetaux. Vol. 34, Pg. 17, 1980. | |
| (+-)-2,4'-Dichloro-alpha-(pyrimidin-5-yl)benzhydryl alcohol | (+/-)-Fenarimol | (2-Chlorophenyl)(4-chlorophenyl)(pyrimidin-5-yl)methanol |
| (2-Chlorophenyl)(4-chlorophenyl)5-pyrimidinylmethanol # | (2-Chlorophenyl)-.alpha.-(4-chlorophenyl)-5-pyrimidinemethanol | (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol |
| (2-chlorophenyl)-(4-chlorophenyl)-pyrimidin-5-ylmethanol | (4-Chloro-phenyl)-(2-chloro-phenyl)-pyrimidin-5-yl-methanol | .alpha.-(2-Chlorophenyl)-.alpha.-(4-chlorophenyl)-5-pyrimidinemethanol |
| 168F889 | 2,4'-Dichloro-(pyrimidin-5-yl)benzhydryl alcohol | 2,4'-Dichloro-alpha(pyrimidin-5-yl)benzhydryl alcohol |
| 2,4'-dichloro-a(pyrimidin-5-yl)benzhydryl alcohol | 5-Pyrimidinemethanol, .alpha.-(2-chlorophenyl)-.alpha.-(4-chlorophenyl)- | 5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)- |
| 5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)- (9CI) | 60168-88-9 | AKOS015895790 |
| AX8130183 | BDBM50024511 | BLOC |
| BRN 5972869 | C-20045 | C11226 |
| CAS-60168-88-9 | CC-28369 | CHEBI:83686 |
| CHEMBL28971 | Caswell No. 207AA | Compound 56722 |
| DB-053545 | DNDI1246778 | DSSTox_CID_12390 |
| DSSTox_GSID_32390 | DSSTox_RID_78935 | DTXSID2032390 |
| EINECS 262-095-7 | EL 222 | EPA Pesticide Chemical Code 206600 |
| FENARIMOL | FT-0630719 | Fenarimol 10 microg/mL in Cyclohexane |
| Fenarimol 10 microg/mL in Ethyl acetate | Fenarimol 100 microg/mL in Cyclohexane | Fenarimol [ANSI:BSI:ISO] |
| Fenarimol, PESTANAL(R), analytical standard | LS-135442 | NCGC00163917-01 |
| NCGC00163917-02 | NCGC00163917-03 | NCGC00163917-04 |
| NCGC00163917-05 | NCGC00254558-01 | NCGC00259180-01 |
| NHOWDZOIZKMVAI-UHFFFAOYSA-N | Pesticide6_Fenarimol_C17H12Cl2N2O_(2-Chlorophenyl)(4-chlorophenyl)5-pyrimidinylmethanol; | PubChem16971 |
| Q906987 | Rimidin | Rubigan |
| SC-81548 | SCHEMBL42209 | Tox21_201631 |
| Tox21_300650 | W-111179 | alpha-(2-Chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol |
| alpha-(2-Chlorophenyl)-alpha-4-(chlorophenyl)-5-pyrimidinemethanol |