Compound
D0927 | fendiline hydrochloride
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 10.34±1.55 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 9.75 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P301+P312, P330, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| 13636-18-5 | 3,3-diphenyl-N-(1-phenylethyl)-1-propanamine hydrochloride | 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine hydrochloride |
| 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;hydrochloride | A807067 | AKOS030526089 |
| API0008517 | Benzenepropanamine, gamma-phenyl-N-(1-phenylethyl)-, hydrochloride (1:1); | C-20665 |
| CAS-13636-18-5 | CCG-40224 | CHEMBL1405922 |
| CS-4475 | CTK8F9736 | D07943 |
| DB-042340 | DSSTox_CID_25860 | DSSTox_GSID_45860 |
| DSSTox_RID_81180 | DTXSID2045860 | FT-0630407 |
| Fendiline (hydrochloride) | Fendiline HCl | Fendiline hydrochloride |
| Fendiline(hydrochloride) | HMS1568F22 | HMS1921D11 |
| HY-B0984 | J-006837 | KS-00001F9U |
| MLS000069570 | MLS001076126 | MLS002222223 |
| N-(3,3-Diphenylpropyl)-?-methylbenzylamine hydrochloride | NCGC00018223-06 | NCGC00094891-01 |
| NCGC00094891-02 | NCGC00094891-03 | NCGC00094891-04 |
| NSC-757826 | NSC757826 | Opera_ID_555 |
| Pharmakon1600-01501026 | Prestwick_568 | Q27279890 |
| REGID_for_CID_5702162 | SCHEMBL666530 | SMR000058827 |
| SPECTRUM1501026 | SR-01000003123 | SR-01000003123-3 |
| SR-01000003123-4 | Sensit (TN) | Tox21_111351 |
| Tox21_111351_1 | fendiline-hydrochloride | s5279 |