Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 25.85±1.87 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | human | HepG2 | MMP assay | Negative | IC50 | 163 | ||
MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Danger |
Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P301+P310, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
078RCY7I27 | 1-(3-Chloro-phenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)-urea | 1-(3-chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea |
57653-26-6 | AKOS022488647 | B7035 |
BDBM50105838 | BN0209 | BRD-K41160163-001-01-9 |
C-16725 | CAS-57653-26-6 | CC-28382 |
CHEBI:92728 | CHEMBL239800 | CS-0021515 |
DB12931 | DSSTox_CID_26770 | DSSTox_GSID_46770 |
DSSTox_RID_81892 | DTXSID5046770 | Fenobam |
Fenobam [INN] | Fenobamum | Fenobamum [INN-Latin] |
HMS3413I16 | HMS3677I16 | HY-101478 |
LS-193274 | MCN 3377-98 | MCULE-9260864714 |
MFCD00868019 | McN-3377-98 | N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea |
N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea; | NCGC00092384-01 | NCGC00092384-02 |
NCGC00092384-03 | NCGC00261527-01 | NPL 2009 |
Tox21_112624 | Tox21_112624_1 | Tox21_113516 |
Tox21_500842 | UNII-078RCY7I27 | Urea, N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)- |
fenobam anhydrous | n-(3-chlorophenyl)-n'-(1-methyl-4-oxo-4,5-dihydro-1h-imidazol-2-yl)urea |
CAS Number | 57653-26-6, 63540-28-3, 7255-99-4, 7256-23-7 |
PubChem Compound | 135659063 |