Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 28.92±16.69 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 11.22 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 21.29±17.89 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Warning |
Aggregated GHS information provided by 39 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
(Indol-3-yl)pyruvate | (indol-3-yl)pyruvic acid | .beta.-Indolepyruvic acid |
.beta.-Indolylpyruvic acid | 1H-Indole-3-propanoic acid, .alpha.-oxo- | 1H-Indole-3-propanoic acid, alpha-oxo- |
1H-Indole-3-propanoic acid, alpha-oxo- (9CI) | 1H-Indole-3-propanoicacid, a-oxo- | 1H-Indole-3-pyruvic acid |
3-(1H-Indol-3-yl)-2-oxopropanoic acid | 3-(1H-indol-3-yl)-2-keto-propionic acid | 3-(1H-indol-3-yl)-2-oxidanylidene-propanoic acid |
3-(3-Indolyl)-2-oxopropanoic acid | 3-(3-Indolyl)-2-oxopropanoic acid | 3-(3-Indolyl)-2-oxopropanoic acid |
3-(indol-3-yl)pyruvic acid | 3-Indolepyruvic acid | 3-Indolpyruvic acid |
3-Indolylpyroracemic acid | 3-Indolylpyruvic acid | 3-Indolylpyruvic acid |
3-Indolylpyruvic acid | 3-indol-3-yl-2-oxopropanoic acid | 3-indole-pyruvic acid |
35656-49-6 | 392-12-1 | 392I121 |
3IO | 4QM0LT13A8 | 5-22-06-00324 (Beilstein Handbook Reference) |
AB1011912 | AC-10208 | AC17FD8D-94BC-4C87-B5E6-D2B60F03B45D |
AKOS005267243 | ANW-46652 | ARONIS24313 |
AS-63461 | BRN 0172966 | C00331 |
CAS-392-12-1 | CHEBI:29750 | CHEMBL485012 |
CI-014 | CTK4I1112 | DSSTox_CID_22053 |
DSSTox_GSID_42053 | DSSTox_RID_79908 | DTXSID3042053 |
EBD45217 | EINECS 206-874-1 | F9995-2651 |
FT-0627222 | HMS2270A21 | I-4200 |
Indol-3-ylpyruvic acid | Indole pyruvic acid | Indole-3-pyrubate |
Indole-3-pyruvate | Indole-3-pyruvic acid | Indole-3-pyruvic acid monohydrate |
Indole-3-pyruvic acid, >=98.0% (TLC) | Indolepyruvic acid | Indolyl-3-pyruvate |
KS-000018CS | KS-00004725 | LS-83400 |
MCULE-1073478615 | MLS000515792 | NCGC00247042-01 |
NCGC00255790-01 | NSC 88874 | NSC-88874 |
NSC88874 | PubChem7282 | Q23905803 |
RSTKLPZEZYGQPY-UHFFFAOYSA-N | SBB003515 | SCHEMBL125249 |
SMR000112266 | ST056381 | ST24028266 |
STL286879 | TC-135397 | Tox21_301365 |
UNII-4QM0LT13A8 | VI30400 | ZINC1532617 |
alpha-Oxo-1H-indole-3-propanoic acid | alpha-Oxo-1H-indole-3-propanoic acid; | beta-Indolepyruvic acid |
beta-Indolylpyruvic acid | bmse000646 | bmse000685 |
indol-3-pyruvic acid | indol-3-yl pyruvic acid | indolepyruvate |