Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 14.21±1.82 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 14.13 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Danger |
Aggregated GHS information provided by 526 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 456 of 526 companies. For more detailed information, please visit ECHA C&L website Of the 7 notification(s) provided by 70 of 526 companies with hazard statement code(s): H315 (35.71%): Causes skin irritation [Warning Skin corrosion/irritation] H318 (51.43%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H319 (35.71%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P280, P302+P352, P305+P351+P338, P310, P321, P332+P313, P337+P313, and P362; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
0QQJ25X58G | 2-Methylpropyl 4-Hydroxybenzoate (Isobutyl Parahydroxybenzoate) | 2-Methylpropyl 4-hydroxybenzoate |
3-10-00-00308 (Beilstein Handbook Reference) | 4-Hydroxybenzoic Acid Isobutyl Ester | 4-Hydroxybenzoic acid, 2-methylpropyl ester |
4-Hydroxybenzoic acid-iso-butyl ester 100 microg/mL in Acetonitrile | 4-Hydroxybenzoic acid-isobutyl ester | 4247-02-3 |
ACMC-2097ew | AK114266 | AKOS000319531 |
ANW-13878 | ARONIS013135 | AS-15247 |
BENZOIC ACID, p-HYDROXY-, ISOBUTYL ESTER | BIDD:ER0110 | BRN 2642305 |
Benzoic acid, 4-hydroxy-, 2-methylpropyl ester | Benzoic acid, 4-hydroxy-, 2-methylpropyl ester (9CI) | Butyl parahydroxybenzoate impurity E, European Pharmacopoeia (EP) Reference Standard; |
C20342 | CAS-4247-02-3 | CCRIS 2463 |
CHEMBL3182006 | CTK3I9889 | ChemDiv2_000057 |
DB-070303 | DSSTox_CID_749 | DSSTox_GSID_20749 |
DSSTox_RID_75767 | DTXSID4020749 | EINECS 224-208-8 |
EU-0033430 | FT-0618696 | HMS1369C13 |
I0816 | ISOBUTYL PARA HYDROXY BENZOATE | Isobutyl 4-hydroxybenzoate |
Isobutyl 4-hydroxybenzoate, 97% | Isobutyl p-hydroxybenzoate | Isobutyl parahydroxybenzoate |
Isobutyl-4-hydroxy benzoate | Isobutyl-4-hydroxybenzoate | Isobutyl4-hydroxybenzoate |
Isobutylparaben | KS-00000VPJ | KS-000043VJ |
KSC489Q8T | LS-7460 | MCULE-4335589438 |
MFCD00020167 | Methylpropyl p-hydroxybenzoate | NCGC00248662-01 |
NCGC00258055-01 | O620 | Q27237117 |
RTR-016620 | SBB080168 | SCHEMBL34633 |
SR-01000389342 | SR-01000389342-1 | ST24047425 |
ST45049845 | STL067196 | TR-016620 |
TRA0067808 | Tox21_200501 | UNII-0QQJ25X58G |
W-106272 | XPJVKCRENWUEJH-UHFFFAOYSA-N | ZINC225900 |
isobutyl paraben | p-Hydroxybenzoic acid iso-butyl ester | p-Hydroxybenzoic acid isobutyl ester |
p-Hydroxybenzoic acid sec-butyl ester | p-Oxybenzoesaureisobutylester | p-Oxybenzoesaureisobutylester [German] |