D0966 | isoxaben
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 26.32±5.75 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 14.13 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
|
H413: May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] |
P273, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | ||
|
Aggregated GHS information provided by 192 companies from 1 notifications to the ECHA C&L Inventory. H413 (100%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P273, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | ||
 |
Warning |
Aggregated GHS information provided by 56 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H400 (98.21%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (98.21%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P273, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
H413: May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] |
P273, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | ||
  |
Warning |
H315: Causes skin irritation [Warning Skin corrosion/irritation] H320: Causes eye irritation [Warning Serious eye damage/eye irritation] H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] |
P201, P202, P264, P280, P281, P302+P352, P305+P351+P338, P308+P313, P321, P332+P313, P337+P313, P362, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| 101V41EEA4 | 2,6-Dimethoxy-N-(3-(1-ethyl-1-methylpropyl)-5-isoxazolyl)benzamide | 2,6-dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide |
| 82558-50-7 | Benzamide, 2,6-dimethoxy-N-(3-(1-ethyl-1-methylpropyl)-5-isoxazolyl)- | Benzamide, N-(3-(1-ethyl-1-methylpropyl)-5-isoxazolyl)-2,6-dimethoxy- |
| Benzamide, N-[3-(1-ethyl-1-methylpropyl)-5-isoxazolyl]-2,6-dimethoxy- | Benzamizole | C-20085 |
| C18504 | CAS-82558-50-7 | CC-29728 |
| CHEBI:63956 | CHEMBL2142789 | CTK8G0402 |
| Caswell No. 419F | Cent 7 | Compound 121607 |
| DB-056630 | DSSTox_CID_4159 | DSSTox_GSID_24159 |
| DSSTox_RID_77309 | DTXSID8024159 | EC 407-190-8 |
| EL 107 | EPA Pesticide Chemical Code 125851 | FT-0630906 |
| Flexidor | Gallery | HSDB 6691 |
| InChI=1/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21); | Isoxaben | Isoxaben 100 microg/mL in Methanol |
| Isoxaben [BSI:ISO] | Isoxaben, PESTANAL(R), analytical standard | Knot out |
| LS-26561 | N-(3-(1-Ethyl-1-methylpropyl)-1,2-oxazol-5-yl)-2,6-dimethoxybenzamide | N-(3-(1-Ethyl-1-methylpropyl)-5-isoxazolyl)-2,6-dimethoxybenzamide |
| N-(3-(1-Ethyl-methylpropyl)-5-isoxazolyl)-2,6-dimethoxybenzamide | N-[3-(1-Ethyl-1-methylpropyl)-5-isoxazolyl]-2,6-dimethoxybenzamide | N-[3-(1-ethyl-1-methylpropyl)isoxazol-5-yl]-2,6-dimethoxybenzamide |
| N-[3-(1-ethyl-1-methylpropyl]-5-isoxazolyl]-2,6-dimethoxybenzamide | NA 8318 | NCGC00164275-01 |
| NCGC00164275-02 | NCGC00164275-03 | NCGC00164275-04 |
| NCGC00254604-01 | NCGC00259123-01 | PMHURSZHKKJGBM-UHFFFAOYSA- |
| PMHURSZHKKJGBM-UHFFFAOYSA-N | Prolan (herbicide) | Q2677285 |
| SCHEMBL54432 | Tox21_201574 | Tox21_300696 |
| UNII-101V41EEA4 | X-Pand | ZINC2004090 |