Drug

D0981 | lufenuron

Molecular Formula C17H8Cl2F8N2O3
Molecular Weight 511.1
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 7.65±0.70 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 14.13 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 44.96±7.29 rat hepatocytes MMP assay decrease IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Warning

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

Aggregated GHS information provided by 193 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]


H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

Aggregated GHS information provided by 4 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]


H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]


H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]


H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]


P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Warning

H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]


H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]


P201, P202, P260, P281, P308+P313, P314, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 055L078 1-(2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea 103055-07-8
    130841-22-4 130841-26-8 4629851K7Q
    9CR45YMS74 AB01563233_01 AB2000759
    AK117729 AKOS022185021 AS-13363
    BCP15961 BRD-A71774530-001-01-8 BRD-A71774530-001-02-6
    BSPBio_002424 Benzamide, N-(((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)amino)carbonyl)-2,6-difluoro-, (+)- Benzamide, N-(((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)amino)carbonyl)-2,6-difluoro-, (-)-
    Benzamide, N-[[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluoro- Benzamide,N-[[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]carbonyl]-2,6-difluoro-; C-23005
    C17H8Cl2F8N2O3 C18434 CAS-103055-07-8
    CC-30083 CCG-213976 CGA 184699
    CHEBI:39384 CHEMBL1364906 Cigna
    D08150 DB-040412 DB11424
    DSSTox_CID_14357 DSSTox_GSID_34357 DSSTox_RID_79146
    DTXSID5034357 EC 410-690-9 FT-0631021
    Fluphenacur H999 HMS3264N09
    J-521659 Lufenuron Lufenuron (INN)
    Lufenuron [INN:BAN] Lufenuron for peak identification, European Pharmacopoeia (EP) Reference Standard Lufenuron, (+)-
    Lufenuron, (-)- Lufenuron, European Pharmacopoeia (EP) Reference Standard Lufenuron, PESTANAL(R), analytical standard
    Lufenuron, United States Pharmacopeia (USP) Reference Standard Lufenurone Lufenurone [INN-French]
    Lufenuronum Lufenuronum [INN-Latin] MLS004712069
    Match (pesticide) N-((2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)carbamoyl)-2,6-difluorobenzamide N-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)-phenyl-aminocarbonyl)-2,6-difluorobenzamide
    N-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylcarbamoyl)-2,6-difluorobenzamide N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide N-[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluoro-benzamide
    N-[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluorobenzamide N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide NCGC00095978-01
    NCGC00095978-02 NCGC00095978-03 NCGC00095978-04
    NCGC00095978-06 NCGC00254811-01 NSC-759097
    NSC759097 PWPJGUXAGUPAHP-UHFFFAOYSA-N Pharmakon1600-01505355
    Program [veterinary] (TN) Program flavor tabs Q412933
    SBI-0207025.P001 SC-14159 SCHEMBL27105
    SMR001563631 SPECTRUM1505355 SR-01000872762
    SR-01000872762-1 ST24048228 Tox21_111542
    Tox21_111542_1 Tox21_300907 UNII-4629851K7Q
    UNII-9CR45YMS74 VA11207

    DrugBank Name lufenuron
    DrugBank DB11424
    CAS Number 103055-07-8, 130841-22-4, 130841-26-8
    PubChem Compound 71777
    KEGG Compound ID C18434
    KEGG Drug D08150
    ChEBI 39384