Drug

D0982 | lynestrenol

Molecular Formula C20H28O
Molecular Weight 284.4
Structure

G

G03FB02 Lynestrenol and estrogen


[G03FB] Progestogens and estrogens, sequential preparations


[G03F] PROGESTOGENS AND ESTROGENS IN COMBINATION


[G03] SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM


[G] Genitourinary system and reproductive hormones


G03FA07 Lynestrenol and estrogen


[G03FA] Progestogens and estrogens, fixed combinations


[G03F] PROGESTOGENS AND ESTROGENS IN COMBINATION


[G03] SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM


[G] Genitourinary system and reproductive hormones


G03DC03 Lynestrenol


[G03DC] Estren derivatives


[G03D] PROGESTOGENS


[G03] SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM


[G] Genitourinary system and reproductive hormones


G03AC02 Lynestrenol


[G03AC] Progestogens


[G03A] HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE


[G03] SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM


[G] Genitourinary system and reproductive hormones


G03AB02 Lynestrenol and ethinylestradiol


[G03AB] Progestogens and estrogens, sequential preparations


[G03A] HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE


[G03] SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM


[G] Genitourinary system and reproductive hormones


G03AA03 Lynestrenol and ethinylestradiol


[G03AA] Progestogens and estrogens, fixed combinations


[G03A] HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE


[G03] SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM


[G] Genitourinary system and reproductive hormones


Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 16.63±2.15 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 7.4 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 18 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H302 (94.44%): Harmful if swallowed [Warning Acute toxicity, oral]


H312 (88.89%): Harmful in contact with skin [Warning Acute toxicity, dermal]


H332 (88.89%): Harmful if inhaled [Warning Acute toxicity, inhalation]


H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]


H360 (94.44%): May damage fertility or the unborn child [Danger Reproductive toxicity]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P312, P322, P330, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • (17-alpha)-19-Norpregn-4-en-20-yn-17-ol (17alpha)-17-ethynylestr-4-en-17-ol (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol
    .DELTA.4-17.alpha.-Ethinylestren-17.beta.-ol 052L766 17-Ethynylestr-4-en-17-ol
    17-alpha-Ethinyl-17-beta-hydroxyestr-4-ene 17-alpha-Ethinyl-17-beta-hydroxyoestr-4-ene 17-alpha-Ethynil-delta-4-estrene-17-beta-ol
    17-alpha-Ethynylestr-4-en-17-beta-ol 17-alpha-Ethynylestrenol 17-alpha-Ethynyloestr-4-en-17-beta-ol
    17-alpha-Ethynyloestrenol 17.alpha.-Ethynylestrenol 17alpha-Ethynylestrenol
    19 Norpregn-4-en-20-yn-17-ol, (17alpha)- 19-Nor-17-alpha-pregn-4-en-20-yn-17-ol 19-Nor-17.alpha.-pregn-4-en-20-yn-17-ol
    19-Nor-17alpha-pregn-4-en-20-yn-17-ol 19-Nor-17alpha-pregn-4-en-20-yn-17-ol (8CI) 19-Nor-4-pregnen-20-yn-17beta-ol
    19-Norpregn-4-en-20-yn-17-ol, (17.alpha.)- 19-Norpregn-4-en-20-yn-17-ol, (17a)- 19-Norpregn-4-en-20-yn-17-ol, (17alpha)-
    19-norpregn-4-en-20-yn-17alpha-ol 3-Desoxynorlutin 52-76-6
    AK161684 AKOS024462708 BCP04136
    BPBio1_000056 BSPBio_000050 C13037
    CCG-220095 CCRIS 9093 CHEBI:31790
    CHEMBL2107431 D01580 DB12474
    EINECS 200-151-4 Endometril Estr-4-en-17.beta.-ol, 17-ethynyl-
    Estr-4-en-17beta-ol, 17-ethynyl- Ethinyl oestrenol Ethinylestrenol
    Ethinyloestranol Ethynloestrenol Ethynylestrenol
    Exluten Exlution Exluton
    Exlutona HMS1568C12 HMS2095C12
    HMS3712C12 HSDB 7899 IND 1006
    L0246 LMST02030127 LS-7125
    LYNESTRENOL Linesterol Linestrenol
    Linestrenol [INN-Spanish] Linestrenolo Linestrenolo [DCIT]
    Lynenol Lynestrenol (JAN/USAN) Lynestrenol [USAN:INN:BAN:JAN]
    Lynestrenol [USAN:INN:JAN] Lynestrenolum Lynestrenolum [INN-Latin]
    Lynoestrenol Lynoestrenol [Progestins] Lynstranol
    N2Z8ALG4U5 NCGC00179676-01 NSC 37725
    NSC-37725 NSC-73879 NSC37725
    NSC73879 Org 485-50 Orgametil
    Orgametril Orgametrol Prestwick0_000095
    Prestwick1_000095 Prestwick2_000095 Prestwick3_000095
    Prestwick_533 Q2071071; SC-47263
    SCHEMBL37816 SPBio_001989 ST24047514
    UNII-N2Z8ALG4U5 YNVGQYHLRCDXFQ-XGXHKTLJSA-N ZINC3875355
    delta(sup 4)-17-alpha-Ethinylestren-17-beta-ol delta(sup 4)-17-alpha-Ethinyloestren-17-beta-ol delta4-17alpha-Ethinylestren-17beta-ol
    s4883

    DrugBank Name lynestrenol
    DrugBank DB12474
    CAS Number 52-76-6
    PubChem Compound 5857
    KEGG Compound ID C13037
    KEGG Drug D01580
    ChEBI 31790