Compound

D0983 | lysergide

Molecular Formula C20H25N3O
Molecular Weight 323.4
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 9.03±1.87 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 17.34 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL rat hepatocytes MMP assay Negative IC50 163

Pictogram Signal Statements Precautionary Statement Codes
Danger

Aggregated GHS information provided by 41 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H300 (97.56%): Fatal if swallowed [Danger Acute toxicity, oral]


H310 (97.56%): Fatal in contact with skin [Danger Acute toxicity, dermal]


H330 (97.56%): Fatal if inhaled [Danger Acute toxicity, inhalation]


H351 (97.56%): Suspected of causing cancer [Warning Carcinogenicity]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P201, P202, P260, P262, P264, P270, P271, P280, P281, P284, P301+P310, P302+P350, P304+P340, P308+P313, P310, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
Danger

H300: Fatal if swallowed [Danger Acute toxicity, oral]


H310: Fatal in contact with skin [Danger Acute toxicity, dermal]


H330: Fatal if inhaled [Danger Acute toxicity, inhalation]


H351: Suspected of causing cancer [Warning Carcinogenicity]


P201, P202, P260, P262, P264, P270, P271, P280, P281, P284, P301+P310, P302+P350, P304+P340, P308+P313, P310, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 intravenous 46mg/kg (46mg/kg) International Record of Medicine. Vol. 172, Pg. 702, 1959.
human TDLo oral 2857ng/kg (0.002857mg/kg) behavioral: "hallucinations, distorted perceptions" "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 356, 1969.
rabbit LD50 intravenous 300ug/kg (0.3mg/kg) Annals of the New York Academy of Sciences. Vol. 66, Pg. 668, 1957.
human TDLo oral 700ng/kg (0.0007mg/kg) behavioral: excitement Journal of Pharmacology and Experimental Therapeutics. Vol. 120, Pg. 340, 1957.
human TDLo intramuscular 750ng/kg (0.00075mg/kg) Psychopharmacologia Vol. 3, Pg. 219, 1962.
bird - wild LD50 oral 1800ug/kg (1.8mg/kg) Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
human TDLo oral 857ng/kg (0.000857mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 220, 1966.
rat LD50 intravenous 16mg/kg (16mg/kg) International Record of Medicine. Vol. 172, Pg. 702, 1959.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg) National Technical Information Service. Vol. AD277-689,
guinea pig LD50 subcutaneous 16mg/kg (16mg/kg) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 137, Pg. 375, 1962.


  • (+)-LSD (+)-Lysergic acid diethylamide (4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide
    (6aR,9R)-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (6aR,9R)-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide (8R)-9,10-didehydro-N,N-diethyl-6-methylergoline-8-carboxamide
    (8alpha)-N,N-Diethyl-6-Methyl-9,10-Didehydroergoline-8-Carboxamide (8beta)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide 4-25-00-00939 (Beilstein Handbook Reference)
    50-37-3 6482-EP1441224A2 6482-EP2311494A1
    6482-EP2311801A1 6482-EP2311802A1 6482-EP2311803A1
    6482-EP2371814A1 752-EP2269986A1 752-EP2270004A1
    752-EP2270006A1 752-EP2270014A1 752-EP2270016A1
    752-EP2272537A2 752-EP2272822A1 752-EP2272834A1
    752-EP2272842A1 752-EP2272972A1 752-EP2272973A1
    752-EP2275403A1 752-EP2275411A2 752-EP2275417A2
    752-EP2277866A1 752-EP2277872A1 752-EP2281812A1
    752-EP2282982A1 752-EP2284162A2 752-EP2284163A2
    752-EP2284178A2 752-EP2284179A2 752-EP2286811A1
    752-EP2287153A1 752-EP2287155A1 752-EP2289868A1
    752-EP2289885A1 752-EP2292228A1 752-EP2292589A1
    752-EP2292613A1 752-EP2292619A1 752-EP2292624A1
    752-EP2295402A2 752-EP2295406A1 752-EP2295407A1
    752-EP2295410A1 752-EP2295411A1 752-EP2298731A1
    752-EP2298735A1 752-EP2298736A1 752-EP2298745A1
    752-EP2298761A1 752-EP2298763A1 752-EP2298767A1
    752-EP2298770A1 752-EP2298772A1 752-EP2298777A2
    752-EP2298783A1 752-EP2301627A1 752-EP2301918A1
    752-EP2301928A1 752-EP2301929A1 752-EP2301935A1
    752-EP2301937A1 752-EP2305033A1 752-EP2305640A2
    752-EP2305648A1 752-EP2305650A1 752-EP2305652A2
    752-EP2305663A1 752-EP2305666A1 752-EP2305673A1
    752-EP2305674A1 752-EP2305685A1 752-EP2305686A1
    752-EP2308838A1 752-EP2308839A1 752-EP2308847A1
    752-EP2308848A1 752-EP2308849A1 752-EP2308850A1
    752-EP2308861A1 752-EP2308867A2 752-EP2308870A2
    752-EP2308871A1 752-EP2308873A1 752-EP2311808A1
    752-EP2311825A1 752-EP2311829A1 752-EP2311834A1
    752-EP2311842A2 752-EP2311850A1 752-EP2314571A2
    752-EP2314581A1 752-EP2314587A1 752-EP2316470A2
    752-EP2316831A1 752-EP2316832A1 752-EP2316833A1
    752-EP2371797A1 752-EP2371798A1 752-EP2371800A1
    752-EP2371804A1 752-EP2374786A1 752-EP2374787A1
    752-EP2377849A2 7LD; 8NA5SWF92O
    9,10-Didehydro-N,N-diethyl-6-methyl-ergoline-8-beta-carboxamide 9,10-Didehydro-N,N-diethyl-6-methylergoline-8b-carboxamide Acid [Street Name]
    BDBM21342 BDBM50241702 BRN 0094179
    Barrels Bart Simpson Bartman
    Beast Big F Blotter Acid
    Blue Acid Blue Cheer Blue Mist
    Blue Star Brown Dots C07542
    CAS-50-37-3 CHEBI:6605 CHEMBL263881
    CHEMBL463207 California Sunshine Cherry Top
    Chief Chocolate Chips Clearlight
    Contact Lens Cubes Cubes [Street Name]
    Cupcakes D-Lsd D-Lysergic acid diethylamide
    DB04829 DEA No. 7315 DSSTox_CID_3231
    DSSTox_GSID_23231 DSSTox_RID_76934 DTXSID1023231
    Delysid Diethylamid kyseliny lysergove Diethylamid kyseliny lysergove [Czech]
    Domes EINECS 200-033-2 Ergoline-8-beta-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-
    Ergoline-8-beta-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-, (-)- Ergoline-8-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-, (8b)- Ergoline-8-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-, (8beta)-
    Ergoline-8b-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl- (8CI) Ergoline-8beta-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl- FT-0670891
    Fifty Flats Frogs
    GTPL17 Gelatin Chips Greenies
    HSDB 3920 Hawk Haze
    Heavenly Blue Heavenly Blue [Street Name] Indolo[4,3-fg]quinoline, ergoline-8-carboxamide deriv.
    Instant Zen KE42000000 LS-64351
    LSD LSD (Lysergic Acid Diethylamide) 0.025 mg/ml in Acetonitrile LSD (Lysergic Acid Diethylamide) 1.0 mg/ml in Acetonitrile
    LSD (Lysergic Acid Diethylamide;Lysergide) LSD (alkaloid) LSD 25
    LSD solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material LSD solution, 25 mug/mL in acetonitrile, ampule of 1 mL, certified reference material LSD,(+)
    LSD,l- LSD-25 LYSERGIC ACID DIETHYLAMIDE
    Lisergide Lisergide [DCIT] Lisergido
    Lisergido [INN-Spanish] Lucy in the Sky with Diamonds Lysergamid
    Lysergamide, N,N-diethyl- Lysergaure diethylamid Lysergic acid diethylamide tartrate ci
    Lysergic acid diethylamide, l-isomer Lysergic acid diethylamide-25 Lysergide
    Lysergide [INN:BAN:DCF] Lysergidum Lysergidum [INN-Latin]
    Lysergsaeurediaethylamid Lysergsaeurediethylamid Lysergsauerediaethylamid
    Mean Green Mellow Yellow Microdots
    N,N-Diethyl-(+)-Lysergamide N,N-Diethyl-D-lysergamide N,N-Diethyllysergamide
    NCGC00168265-01 NCGC00168265-02 NIOSH/KE4200000
    Orange Mushroom Orange Sunshine Orange Wedges
    Owsley PDSP1_001431 PDSP1_001540
    PDSP2_001415 PDSP2_001524 Paper Acid
    Pearly gates Pearly gates [Street Name] Purple Haze
    Purple Microdot Q23118 Royal Blue [Street Name]
    Royal blue SCHEMBL113755 Scapes
    Spoonies Strawberry Fields Sugar Lump
    Sunshine The Hawk Tox21_112872
    Tox21_113508 Trippers UNII-8NA5SWF92O
    Ubergluben VAYOSLLFUXYJDT-RDTXWAMCSA-N Wedding Bells Acid
    Wedding bells Wedding bells [Street Name] Wedges
    White Light Window Pane Yellows
    ZINC96903803 [3H]-LSD [N-methyl-3H]LSD

    CAS Number 3184-49-4, 50-37-3
    PubChem Compound 5761
    KEGG Compound ID C07542