Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 2.10±1.87 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 27.48 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 8.67±12.26 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Danger |
Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Danger |
Aggregated GHS information provided by 183 companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301 (40.98%): Toxic if swallowed [Danger Acute toxicity, oral] H302 (59.56%): Harmful if swallowed [Warning Acute toxicity, oral] H318 (96.72%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H361 (96.72%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H400 (96.17%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (96.72%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P264, P270, P273, P280, P281, P301+P310, P301+P312, P305+P351+P338, P308+P313, P310, P321, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] H361d: Suspected of damaging the unborn child [Warning Reproductive toxicity] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P264, P270, P273, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
(4-{[4-(dimethylamino)phenyl]phenylmethylene}cyclohexa-2,5-dienylidene)dimethy lamine, (4-{[4-(dimethylamino)phenyl]phenylmethylene}cyclohexa-2,5-dienylidene )dimethylamine, ethanedioic acid, ethanedi | (4-{[4-(dimethylamino)phenyl]phenylmethylene}cyclohexa-2,5-dienylidene)dimethy lamine, (4-{[4-(dimethylamino)phenyl]phenylmethylene}cyclohexa-2,5-dienylidene )dimethylamine, ethanedioic acid, ethanedioic acid, ethanedioic acid | 13425-25-7 |
2437-29-8 | AKOS015910564 | Ammonium, (4-(p-(dimethylamino)-alpha-phenylbenzylidene)-2,5-cyclohexadien-1-ylidene)-dimethyl-, oxalate (2:1), oxalate (1:1) |
Basic Green 4 | Bis (N-{4-[[4-(dimethylamino)phenyl](phenyl)methylene]cyclohexa-2,5-dien-1-ylidene}-N-methylmethanaminium) trioxalate | Bis((4-(4-(dimethylamino)benzhydrylidene)cyclohexa-2,5-dien-1-ylidene)dimethylammonium) oxalate, dioxalate |
Bis[[4-[4-(dimethylamino)benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium] oxalate, dioxalate | C.I. 4200 | CAS-2437-29-8 |
CHEMBL1545634 | DSSTox_CID_5513 | DSSTox_GSID_25513 |
DSSTox_RID_77817 | DTXSID6025513 | EINECS 219-441-7 |
FT-0628110 | GY1H9O33VU | M0497 |
MCULE-5320008974 | MFCD00011766 | MFCD00151209 |
Malachite Green Oxalate | Malachite Green oxalate salt | Malachite Green oxalate salt (C.I. 42000) |
Malachite Green oxalate, SAJ first grade, >=80.0% | Malachite Green oxalate, pure, certified | Malachite Green oxalate, pure, high purity biological stain |
Malachite Green, Oxalate | Malachite green oxalate 100 microg/mL in Methanol | Methanaminium, N-(4-((4-(dimethylamino)phenyl)phenylmethylene)-2,5-cyclohexadien-1-ylidene)-N-methyl-, ethanedioate (2:2:1); |
Methanaminium, N-(4-((4-(dimethylamino)phenyl)phenylmethylene)-2,5-cyclohexadien-1-ylidene)-N-methyl-, ethanedioate, ethanedioate (2:2:1) | N,N,N',N'-Tetramethyl-4,4'-diaminotriphenylcarbenium oxalate | NCGC00013058-01 |
NCGC00013058-02 | NCGC00091944-01 | NCGC00091944-02 |
NCGC00091944-03 | NCGC00260070-01 | Q27279349 |
SBB058166 | ST51015062 | Tox21_110008 |
Tox21_110008_1 | Tox21_202521 | UNII-GY1H9O33VU |
[4-[[4-(dimethylamino)phenyl]-phenylmethylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium;2-hydroxy-2-oxoacetate;oxalic acid | oic acid, ethanedioic acid |
CAS Number | 13425-25-7, 2437-29-8 |
PubChem Compound | 2724411 |