G
A
D
G04CX03 Mepartricin
[G04CX] Other drugs used in benign prostatic hypertrophy
[G04C] DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
[G04] UROLOGICALS
[G] Genitourinary system and reproductive hormones
G01AA09 Mepartricin
[G01AA] Antibiotics
[G01A] ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
[G01] GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
[G] Genitourinary system and reproductive hormones
D01AA06 Mepartricin
[D01AA] Antibiotics
[D01A] ANTIFUNGALS FOR TOPICAL USE
[D01] ANTIFUNGALS FOR DERMATOLOGICAL USE
[D] Dermatological drugs
A01AB16 Mepartricin
[A01AB] Antiinfectives and antiseptics for local oral treatment
[A01A] STOMATOLOGICAL PREPARATIONS
[A01] STOMATOLOGICAL PREPARATIONS
[A] Alimentary tract and metabolism
Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 23.16±6.59 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 6.9 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 27.66±4.48 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
DrugBank Name | mepartricin |
DrugBank | DB13633 |
CAS Number | 11121-32-7, 62534-68-3 |
PubChem Compound | 9941647 |
KEGG Drug | D04921 |