MITOTOX

Compound

D0994 | methyl triclosan

Properties

Molecular Formula	C13H9Cl3O2
Molecular Weight	303.6
Structure

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Species	Model	Method	Action	Positive criterion	Reference
MEMBRANE POTENTIAL	25.53±1.67	human	qHTS-HepG2	MMP assay	decrease	IC50	163
MEMBRANE POTENTIAL	39.81	human	HepG2	MMP assay	decrease	IC50	163
MEMBRANE POTENTIAL	45.86±14.67	rat	hepatocytes	MMP assay	decrease	IC50	163

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Warning	Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P273, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Warning

Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P273, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Indications Source: SIDER

Synonyms Source: PubChem

2,4,4'-Trichloro-4'-methoxydiphenyl ether	2,4-dichloro-1-(4-chloro-2-methoxyphenoxy)benzene	4-Chloro-1-(2,4-dichlorophenoxy)-2-methoxybenzene #
4640-01-1	5174UR1DP5	AK549015
BRD-K62328564-001-01-1;	Benzene, 4-chloro-1-(2,4-dichlorophenoxy)-2-methoxy-	CAS-4640-01-1
CHEMBL2325395	CTK8G3591	DS-19481
DSSTox_CID_27850	DSSTox_GSID_47874	DSSTox_RID_82603
DTXSID0047874	FT-0675460	KS-00000TVS
Methyl triclosan	Methyltriclosan	NCGC00248561-01
NCGC00257753-01	NLYDHBBTVWMLFD-UHFFFAOYSA-N	Q1925612
SCHEMBL676629	Tox21_200199	Triclosan Methyl Ether
Triclosan methyl	Triclosan-methyl	Triclosan-methyl ether
Triclosan-methyl, analytical standard	UNII-5174UR1DP5	ZINC2526438

External IDs

CAS Number	4640-01-01 00:00:00
PubChem Compound	627458