Compound

D1000 | metochalcone

Molecular Formula C18H18O4
Molecular Weight 298.3
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MEMBRANE POTENTIAL 18.18±10.11 human qHTS-HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 39.81 human HepG2 MMP assay decrease IC50 163
MEMBRANE POTENTIAL 25.48±18.19 rat hepatocytes MMP assay decrease IC50 163

Organism Test type Route Dose (normalized dose) Effect Source
mouse LDLo subcutaneous 7gm/kg (7000mg/kg) Therapie. Vol. 13, Pg. 668, 1958.


  • (2E)-1-(2,4-Dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (E)-1-(2'',4''-Dimethoxyphenyl)-3-(4''''-methoxyphenyl)prop-2-en-1-one (E)-1-(2,4-Dimethoxy-phenyl)-3-(4-methoxy-phenyl)-propenone
    (E)-1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 1-(2,4-Dimethoxy-phenyl)-3-(4-methoxy-phenyl)-propenone 1-(2,4-Dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one
    1314 CB 1314-CB 1754ZE4075
    18493-30-6 2',4'-Trimethoxychalcone 2',4,4'-Trimethoxy-trans-chalcone
    2',4,4'-Trimethoxychalcone 2',4,4'-trimeth-oxychalcone 2-Propen-1-one, 1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)- (9CI)
    2-Propen-1-one, 1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-, (2E)- 2-Propen-1-one,4-dimethoxyphenyl)-3-(4-methoxyphenyl)- 30925-62-3;
    AB00053250-08 AB00053250-10 ACM18493306
    AKOS001024014 BDBM50107308 CHEMBL36584
    Chalcone, 2',4,4'-trimethoxy- Chemicol EINECS 242-377-6
    Gebyl HMS2270C09 Lesidrin
    MLS001049137 Megalip Metocalcona
    Metocalcona [INN-Spanish] Metochalcon Metochalcone
    Metochalcone [INN:DCF] Metochalconum Metochalconum [INN-Latin]
    NCGC00160442-01 NSC 97905 NSC-97905
    NSC97905 Q27251868 SCHEMBL309111
    SMR000386963 SR-01000025297 SR-01000025297-1
    STL513032 Solvocolo Spechol
    Trimecolo Trimepaton Trimethoxy 4-2'-4' chalcone
    Trimethoxy 4-2'-4' chalcone [French] UNII-1754ZE4075 Vesidril
    Vesidryl ZINC3979084

    CAS Number 18493-30-6, 18960-94-6, 30925-62-3
    PubChem Compound 6063342
    ChEBI 135259