Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 15.36±10.52 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 28.18 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 17.77±25.05 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Danger |
Aggregated GHS information provided by 47 companies from 5 notifications to the ECHA C&L Inventory. Reported as not meeting GHS hazard criteria by 2 of 47 companies. For more detailed information, please visit ECHA C&L website Of the 4 notification(s) provided by 45 of 47 companies with hazard statement code(s): H311 (86.67%): Toxic in contact with skin [Danger Acute toxicity, dermal] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P280, P302+P352, P312, P322, P361, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Danger |
H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H401: Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard] H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] |
P273, P280, P302+P352, P312, P322, P361, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | 1gm/kg (1000mg/kg) | Yakkyoku. Pharmacy. Vol. 32, Pg. 605, 1981. | |
rabbit | LD50 | skin | 470mg/kg (470mg/kg) | Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 5, 1978. | |
rat | LD50 | oral | 2800mg/kg (2800mg/kg) | Farm Chemicals Handbook. Vol. -, Pg. C205, 1991. | |
rat | LD50 | skin | 470mg/kg (470mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 139, 1971. | |
113-48-4 | 2-(2-Ethylhexyl)-3a,4,7,7a-tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione | 2-(2-Ethylhexyl)-3a,7,7a-tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione |
2-(2-ethylhexyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione | 4,3(2H)-dione, 2-(2-ethylhexyl)-3a,4,7,7a-tetrahydro- | 4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-(2-ethylhexyl)-3a,4,7,7a-tetra hydro-; |
4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-(2-ethylhexyl)-3a,4,7,7a-tetrahydro- | 4-(2-Ethylhexyl)-4-azatricyclo-[5.2.1.0?,6]dec-8-ene-3,5-dione | 4-(2-ethylhexyl)-4-azatricyclo[5.2.1.0^{2,6}]dec-8-ene-3,5-dione |
5-Norbornene-2, N-(2-ethylhexyl)- | 5-Norbornene-2,3-dicarboximide, N-(2-ethylhexyl)- | AI3-08184 |
AKOS015901672 | AMTGC147 | AS-3197 |
BRN 0025024 | Bicyclo(2.2.1)heptene-2-dicarboxylic acid, 2-ethylhexylimide | Bicyclo[2.2.1]heptene-2-dicarboxylic acid, 2-ethylhexylimide |
C18795 | CAS-113-48-4 | CHEBI:81966 |
CHEMBL1874490 | Carboximide | Caswell No. 613 |
DSSTox_CID_12562 | DSSTox_GSID_32562 | DSSTox_RID_78988 |
DTXSID6032562 | Dicarboximide | EINECS 204-029-1 |
ENT 8,184 | EPA Pesticide Chemical Code 057001 | Endomethylenetetrahydrophthalic acid, N-2-ethylhexyl imide |
Endomethylenetetrahydrophthalic acid, N-2-ethylhexylimide | HSDB 1745 | J-002969 |
KS-000002AI | LS-97203 | MGK 264 |
MGK repellent 264 | MGK-264 | N-(2-Ethylhexyl)-5-norbornene-2,3-dicarboximide |
N-(2-Ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide | N-(2-Ethylhexyl)bicyclo(2.2.1)-5-heptene-2,3-dicarboximide | N-(2-Ethylhexyl)bicyclo-(2,2,1)-hept-5-ene-2,3-dicarboximide |
N-(2-Ethylhexyl)bicyclo-(2.2.1)-5-heptene-2,3-dicarboximide | N-(2-Ethylhexyl)bicyclo[2,1]hept-5-ene-2,3-dicarboximide | N-2-Ethylhexyl bicycloheptenedicarboximide |
N-2-Ethylhexylbicycloheptenedicarboximide | N-2-Ethylhexylimid kyseliny bicyklo-(2,2,1)-5-hepten-2,3-dikarboxylove | N-2-Ethylhexylimid kyseliny bicyklo-(2,2,1)-5-hepten-2,3-dikarboxylove [Czech] |
N-2-Ethylhexylimide endomethylenetetrahydrophthalic acid | N-Octyl bicycloheptene dicarboximide | N-Octyl bicycloheptenedicarboximide |
N-Octylbicyclo-(2.2.1)-5-heptene-2,3-dicarboximide | N-Octylbicyclo[2.2.1]-5-heptene-2,3-dicarboximide | NCGC00168324-01 |
NCGC00168324-02 | NCGC00254690-01 | NSC 36678 |
NSC-36678 | NSC-406879 | NSC36678 |
NSC406879 | Octacide 264 | Octyl bicycloheptenedicarboximide |
Octylbicycloheptenedicarboximide | Pyrdone (obsolete) | Pyrodone |
Q6951386 | SCHEMBL159735 | Sinepyrin 222 |
Synepirin 222 | Synergist 264 | Tox21_300786 |
Van Dyk 264 | WLLGXSLBOPFWQV-UHFFFAOYSA-N | WLN: T C555 A DVNV IUTJ E1Y4 & 2 |
endo Methylenetetrahydrophthalic acid, N-2-ethylhexyl imide |
CAS Number | 113-48-4 |
PubChem Compound | 8227 |