Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 14.78±9.66 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 15.85 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 24.04±16.59 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
1,5-Naphthyridine-3-carboxamide, 6-ethoxy-1,4-dihydro-4-oxo-N-(phenylmethyl)-; | 13BME2F602 | 220860-50-4 |
CAS-220860-50-4 | CHEMBL3184675 | CP-457,920 |
CP-457920 | DGFVZQGXKQCQGK-UHFFFAOYSA-N | DSSTox_CID_27254 |
DSSTox_GSID_47254 | DSSTox_RID_82213 | DTXSID4047254 |
N-benzyl-6-ethoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxamide | N-benzyl-6-ethoxy4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxamide | NCGC00247930-01 |
NCGC00253969-01 | Q27251503 | SCHEMBL6386679 |
Tox21_300208 | UNII-13BME2F602 |
CAS Number | 220860-50-4 |
PubChem Compound | 9831581 |