Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 23.98±12.11 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 25.12 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Danger |
Aggregated GHS information provided by 41 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] H351 (92.68%): Suspected of causing cancer [Warning Carcinogenicity] H372 (92.68%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400 (92.68%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (92.68%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P264, P270, P273, P281, P301+P310, P308+P313, P314, P321, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
---|---|---|---|---|---|
rat | LD | oral | > 1gm/kg (1000mg/kg) | National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 18, 1953. | |
mouse | LD50 | intraperitoneal | 1577mg/kg (1577mg/kg) | Bulletin of Environmental Contamination and Toxicology. Vol. 11, Pg. 359, 1974. | |
mouse | LDLo | oral | 1gm/kg (1000mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 88, Pg. 400, 1946. | |
(-)-1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2,2-trichloroethane | (-)-1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-trichloroethane | (.+/-.)-1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2,2-trichloroethane |
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | 1,1,1-trichloro-2-(2-chloro phenyl)-2-(4-chlorophenyl)ethane | 1,1,1-trichloro-2-(2-chlorophenyl)-2-(4-chlorophenyl)ethane |
1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | 1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2,2-trichloro ethane | 1-Chloro-2-(2,2,2-trichloro-1-(4-chlorophenyl)ethyl)benzene |
1-Chloro-2-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene | 1-Chloro-2-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene # | 2,2,2,o,p'-Pentachloroethylidenebisbenzene |
2,2-Bis(o,p-chlorophenyl)-1,1,1-trichloroethane | 2,4'-(2,2,2-trichloroethane-1,1-diyl)bis(chlorobenzene) | 2,4'-DDT |
2,4'-DDT (1,1,1-Trichloro-2-(p-chlorophenyl)-2-(o-chlorophenyl)ethane) | 2,4'-DDT 10 microg/mL in Cyclohexane | 2,4'-DDT 100 microg/mL in Cyclohexane |
2,4'-DDT 1000 microg/mL in Toluene | 2,4'-DDT solution, 100 mug/mL in methanol, PESTANAL(R), analytical standard; | 2,4'-dichlorodiphenyltrichloroethane |
2,p-chlorophenyl)-1,1,1-trichloroethane | 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1,1-trichloroethane | 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-trichloroethane |
789-02-6 | AI3-03983 | AKOS015902904 |
BDBM50410497 | BRN 1984770 | Benzene, 1-chloro-2-(2,2,2-trichloro-1-(4-chlorophenyl)ethyl)- |
Benzene, 1-chloro-2-(2,2,2-trichloro-1-(4-chlorophenyl)ethyl)- (9CI) | Benzene, 1-chloro-2-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]- | Benzene,2,2-trichloro-1-(4-chlorophenyl)ethyl]- |
C-51970 | C14187 | C14H9Cl5 |
CAS-789-02-6 | CCRIS 9077 | CHEBI:34027 |
CHEMBL364900 | CVUGPAFCQJIYDT-UHFFFAOYSA-N | DDT, o,p'- |
DDT-o,p' | DSSTox_CID_2345 | DSSTox_GSID_22345 |
DSSTox_RID_76554 | DTXSID6022345 | EINECS 212-332-5 |
Ethane, 1,1,1-trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- | Ethane, 1,1,1-trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- (8CI) | Ethane, 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1,1-trichloro- |
Ethane,1,1-trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- | FT-0608457 | LS-65249 |
NCGC00091035-01 | NCGC00091035-02 | NCGC00091035-03 |
NCGC00091035-04 | NCGC00091035-05 | NCGC00091035-06 |
NCGC00254388-01 | NCGC00259788-01 | NSC 33446 |
NSC 57644 | NSC-33446 | NSC-57644 |
NSC33446 | NSC57644 | O,P'-DDT |
Q27115760 | SCHEMBL708196 | Tox21_202239 |
Tox21_300622 | WLN: GXGGYR BG&R DG | o,p-Ddt |
ortho,para'-DDT |