Compound
D1060 | pirenoxine sodium
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 21.13±17.82 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | human | HepG2 | MMP assay | Negative | IC50 | 163 | ||
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 911, 1974. | |
| mouse | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 911, 1974. | |
| rat | LD50 | intraperitoneal | 1460mg/kg (1460mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 911, 1974. | |
| rat | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 911, 1974. | |
| rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 911, 1974. | |
| mouse | LD50 | intraperitoneal | 2120mg/kg (2120mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 911, 1974. | |
| 1-HYDROXY-5-OXO-5H-PYRIDO[3,2-A]PHENOXAZINE-3-CARBOXYLIC ACID MONOSODIUM SALT | 1-Hydroxy-5-oxo-5H-pyrido(3,2-a)phenoxazine-3-carboxylic acid sodium salt | 51410-30-1 |
| 5H-Pyrido(3,2-a)phenoxazine-3-carboxylic acid, 1-hydroxy-5-oxo-, monosodium salt | 5H-Pyrido[3,2-a]phenoxazine-3-carboxylicacid, 1-hydroxy-5-oxo-, sodium salt (1:1); | 95JU7URF64 |
| AB1009549 | ACM51410301 | AKOS015951393 |
| BCP12124 | C16H7N2NaO5 | CAS-51410-30-1 |
| CHEMBL2359957 | Catalin sodium | Clarvisan (TN) |
| D08388 | DSSTox_CID_26637 | DSSTox_GSID_46637 |
| DSSTox_RID_81783 | DTXSID1046637 | EINECS 257-181-6 |
| LS-133976 | NCGC00167452-01 | Pirenoxine sodium |
| Pirenoxine sodium salt | Q27271800 | S468 |
| SCHEMBL11579562 | SCHEMBL1650064 | Sodium 1,5-dioxo-1,5-dihydro-4H-pyrido[3,2-a]phenoxazine-3-carboxylate |
| Sodium 1-hydroxy-5-oxo-5H-pyrido(3,2-a)phenoxazine-3-carboxylate | Sodium 1-hydroxy-5-oxo-5H-pyrido[3,2-a]phenoxazine-3-carboxylate | Tox21_112456 |
| UNII-95JU7URF64 | VA11536 | W-105897 |
| CAS Number | 1043-21-6, 51410-30-1 |
| PubChem Compound | 23695982 |