Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 10.20±6.92 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 4.89 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | 3300mg/kg (3300mg/kg) | lungs, thorax, or respiration: dyspnea | Comptes Rendus des Seances de l'Academie des Sciences, Serie D: Sciences Naturelles. Vol. 263, Pg. 609, 1966. |
1-(2-Hydroxyethyl)-5-nitropyrrole-2-carboxamide | 1-(2-hydroxyethyl)-5-nitro-1h-pyrrole-2-carboxamide | 15960 RP |
2854-09-3 | BRN 0479830 | CTK4G1687 |
DTXSID80951228 | LS-136820; | NP 10 |
NP 10 (Pharmaceutical) | NP-10 | Pyrrole-2-carboxamide, 1-(2-hydroxyethyl)-5-nitro- |
RFQOPUYDLCMQCE-UHFFFAOYSA-N |
CAS Number | 2854-09-3, 6960-07-2, 6960-08-3 |
PubChem Compound | 160655 |