Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 1.66±0.63 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 3.55 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 15.91±5.23 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
Warning |
Aggregated GHS information provided by 41 companies from 3 notifications to the ECHA C&L Inventory. H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P280, P305+P351+P338, and P337+P313; (The corresponding statement to each P-code can be found at the GHS Classification page.) | |
1,7-Diaminoacridine hydrochloride | 2,8-Diaminoacridinium chloride monohydrochloride | 3,6-ACRIDINEDIAMINE, MONOHYDROCHLORIDE |
3,6-Acridinediamine xhydrochloride | 3,6-Acridinediamine, hydrochloride | 3,6-Acridinediamine, hydrochloride (8CI) |
3,6-DIAMINOACRIDINE HCL | 3,6-Diaminoacridine hydrochloride | 3,6-Diaminoacridine hydrochloride hemihydrate |
3,6-Diaminoacridine hydrochloride, Dye content 95 % | 3,6-Diaminoacridine monohydrochloride | 3,6-acridinediamine monohydrochloride |
3,6-diaminoacridine.HCl | 3,6-diaminoacridinium chloride | 51AA3SI0JM |
7459-75-8 | 952-23-8 | AK163704 |
AKOS015894696 | AX8083027 | Acridine, 3,6-diamino-, hydrochloride |
Acridine, 3,6-diamino-, monohydrochloride | CAS-952-23-8 | CCG-35221 |
CCRIS 532 | CHEBI:74718 | CHEMBL606782 |
CHM0157601 | DSSTox_CID_1191 | DSSTox_GSID_21191 |
DSSTox_RID_76001 | DTXSID8021191 | EINECS 213-459-9 |
EINECS 231-239-0 | FT-0699261 | KS-000011NW |
LS-14323 | LS-1998 | MCULE-9156937078 |
NCGC00258067-01 | NCI-C04137 | NSC-605756 |
NSC605756 | PBBGTVBGXBUVLT-UHFFFAOYSA-N | Proflavin hydrochloride |
Proflavine HCl | Proflavine hydrochloride | Proflavine monohydrochloride |
Proflavine.HCl hemihydrate | Q27144855; | SBB003182 |
SCHEMBL664629 | ST24045906 | ST51015092 |
Tox21_200513 | UNII-51AA3SI0JM | acridine-3,6-diamine hydrochloride |
acridine-3,6-diamine, chloride | diacridine-3,6-diamine dihydrochloride hydrate | proflavine hydrochloride hemihydrate |
proflavine monohy drochloride | proflavine.HCl |