Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MEMBRANE POTENTIAL | 26.28±1.71 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 28.18 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
MEMBRANE POTENTIAL | 25.79±10.10 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
Pictogram | Signal | Statements | Precautionary Statement Codes |
---|---|---|---|
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Danger |
Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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Danger |
H300: Fatal if swallowed [Danger Acute toxicity, oral] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] |
P260, P264, P270, P301+P310, P309+P311, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
1-(3-Pyridylmethyl)-3-(4-nitrophenyl)urea | 1-(4-Nitrophenyl)-3-(3-pyridylmethyl)urea | 1-(4-Nitrophenyl)-N'-(3-pyridinylmethyl)urea |
1-(4-nitrophenyl)-3-(pyridin-3-ylmethyl)urea | 3-pyridylmethyl-3-(4-nitrophenyl)urea | 5-22-09-00313 (Beilstein Handbook Reference) |
53558-25-1 | AC-12692 | AKOS003356375 |
BRN 0490322 | CAS-53558-25-1 | CHEMBL1528242 |
CLKZWXHKFXZIMA-UHFFFAOYSA-N | Caswell No. 718B | DB-052359 |
DLP 787 | DSSTox_CID_22360 | DSSTox_GSID_42360 |
DSSTox_RID_80005 | DTXSID1042360 | EINECS 258-626-7 |
EPA Pesticide Chemical Code 104501 | FT-0630661 | HMS2968P19 |
HSDB 6460 | LS-160572 | MCULE-9179018016 |
MLS001232711 | N-(4-Nitrophenyl)-N'-(3-pyridinylmethyl)urea | N-(4-nitrophenyl)-N'-(3-pyridylmethyl)-urea |
N-3-Pyridylmethyl-N'-p-nitrophenylurea | N-3-pyridylmethyl-N'-p-nitrophenyl urea | NCGC00247371-01 |
NCGC00255836-01 | One Time | PYRIMINIL |
Pyriminyl | Pyrinuron | Pyrinuron [ANSI] |
Q7263605 | Q7BGS137YP | RH-787 |
SCHEMBL146250 | SMR000678267 | ST50877271 |
STK494478 | Tox21_302252 | UNII-Q7BGS137YP |
Urea, 1-nitrophenyl-3-(3-pyridylmethyl)- | Urea, N-(4-nitrophenyl)-N'-(3-pyridinylmethyl)- | Vacor |
ZINC5224211 | [(4-nitrophenyl)amino]-N-(3-pyridylmethyl)carboxamide; |
CAS Number | 53558-25-1 |
PubChem Compound | 40813 |