MITOTOX

Compound

D1115 | tetrabutylphosphonium chloride

Properties

Molecular Formula	C16H36ClP
Molecular Weight	294.9
Structure

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Species	Model	Method	Action	Positive criterion	Reference
MEMBRANE POTENTIAL		human	qHTS-HepG2	MMP assay	Negative	IC50	163
MEMBRANE POTENTIAL		human	HepG2	MMP assay	Negative	IC50	163
MEMBRANE POTENTIAL	15.30±5.00	rat	hepatocytes	MMP assay	decrease	IC50	163

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Danger	Aggregated GHS information provided by 42 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (97.62%): Harmful if swallowed [Warning Acute toxicity, oral] H310 (92.86%): Fatal in contact with skin [Danger Acute toxicity, dermal] H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H330 (97.62%): Fatal if inhaled [Danger Acute toxicity, inhalation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P260, P262, P264, P270, P271, P280, P284, P301+P312, P301+P330+P331, P302+P350, P303+P361+P353, P304+P340, P305+P351+P338, P310, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Danger

Aggregated GHS information provided by 42 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H302 (97.62%): Harmful if swallowed [Warning Acute toxicity, oral]

H310 (92.86%): Fatal in contact with skin [Danger Acute toxicity, dermal]

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H330 (97.62%): Fatal if inhaled [Danger Acute toxicity, inhalation]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P260, P262, P264, P270, P271, P280, P284, P301+P312, P301+P330+P331, P302+P350, P303+P361+P353, P304+P340, P305+P351+P338, P310, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Indications Source: SIDER

Synonyms Source: PubChem

2304-30-5	5977P51M7G	ACMC-1CN22
AKOS015907850	ANW-42042	C16H36ClP
CAS-2304-30-5	CHEMBL3186347	CTK3J1516
DSSTox_CID_24616	DSSTox_GSID_44616	DSSTox_RID_80351
DTXSID4044616	EINECS 218-964-8	FT-0657244
IBWGNZVCJVLSHB-UHFFFAOYSA-M	KS-00000VKU	LS-106937
NCGC00257245-01	NCGC00258319-01	Phosphonium, tetrabutyl-, chloride
Phosphonium, tetrabutyl-, chloride (1:1)	Q27261673;	R518
RTR-010768	SCHEMBL124627	T1649
TR-010768	TRA-0183921	Tetra-N-butylphosphonium chloride
Tetrabutyl phosphonium chloride	Tetrabutylphosphonium chloride	Tetrabutylphosphonium chloride 80% solution
Tetrabutylphosphoniumchloride	Tox21_200765	Tox21_303484
UNII-5977P51M7G	W-107439	tetra n-butyl phosphonium chloride
tetrabutylphosphanium,chloride	tetrabutylphosphonium chloride (80% in water)

External IDs

CAS Number	2304-30-5, 3245-41-8
PubChem Compound	75311