D1123 | thidiazuron
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 3.43±0.73 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 6.31 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 4.56±2.78 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
Aggregated GHS information provided by 199 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H312 (98.49%): Harmful in contact with skin [Warning Acute toxicity, dermal] H315 (97.99%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (97.99%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H332 (96.98%): Harmful if inhaled [Warning Acute toxicity, inhalation] H335 (97.99%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P271, P280, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | intraperitoneal | 4200mg/kg (4200mg/kg) | Farm Chemicals Handbook. Vol. -, Pg. C118, 1991. | |
| rat | LC50 | inhalation | > 2300mg/m3/4H (2300mg/m3) | Pesticide Manual. Vol. 9, Pg. 813, 1991. | |
| rabbit | LD50 | oral | 7100mg/kg (7100mg/kg) | behavioral: excitement | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 72, 1984. |
| rabbit | LD50 | skin | > 1gm/kg (1000mg/kg) | Pesticide Manual. Vol. 9, Pg. 813, 1991. | |
| mouse | LD50 | oral | 3740mg/kg (3740mg/kg) | behavioral: excitement | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 72, 1984. |
| rat | LD50 | oral | 5350mg/kg (5350mg/kg) | behavioral: excitement | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 72, 1984. |
| guinea pig | LD50 | oral | 2813mg/kg (2813mg/kg) | behavioral: excitement | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 72, 1984. |
| quail | LD50 | oral | > 16gm/kg (16000mg/kg) | Pesticide Manual. Vol. 9, Pg. 813, 1991. | |
| (N-1,2,3-Thiadiazolyl-5)-N'-phenylurea | (phenylamino)-N-(1,2,3-thiadiazol-5-yl)carboxamide | 0091WH7STF |
| 1-Phenyl-3-(1,2,3-thiadiazol-5-yl)urea | 1-phenyl-3-(1,2,3-thiadiazole-5-yl)-urea | 1-phenyl-3-(5-thiadiazolyl)urea |
| 1-phenyl-3-(thiadiazol-5-yl)urea | 118T836 | 5-Phenylcarbamoylamino-1,2,3-thiadiazole |
| 51707-55-2 | A828736 | AB00079069-01 |
| AB0015469 | AC-14070 | ACM41118836 |
| AK116569 | AKOS000505963 | BDBM50274591 |
| BIT0888 | BRN 1078092 | C18812 |
| CAS-51707-55-2 | CCG-24904 | CHEBI:81977 |
| CHEMBL505661 | CS-0012891 | Cambridge id 5282278 |
| Caswell No. 659A | DB-015552 | DSSTox_CID_12651 |
| DSSTox_GSID_32651 | DSSTox_RID_79026 | DTXSID0032651 |
| Defolit | Dropp | EINECS 257-356-7 |
| EPA Pesticide Chemical Code 120301 | FT-0630649 | GY0412 |
| HF-0028 | HFCYZXMHUIHAQI-UHFFFAOYSA-N | HSDB 7734 |
| J10259 | K-9492 | KS-00000072 |
| LS-160656 | M955 | MCULE-8227703755 |
| MFCD00078723 | N-Phenyl-N'-1,2,3-thiadiazol-5-yl-urea | N-Phenyl-N'-1,2,3-thiadiazol-5-ylurea |
| N-Phenyl-N'-1,2,3-thiazol-5-ylurea | N-phenyl-N'-1,2,3-thiadiazole-5-yl Urea | NCGC00160490-01 |
| NCGC00160490-02 | NCGC00160490-03 | NCGC00160490-04 |
| NCGC00254559-01 | Pesticide2_Thidiazuron_C9H8N4OS_1-Phenyl-3-(1,2,3-thiadiazol-5-yl)urea | Q1968056 |
| SCHEMBL11467912 | SCHEMBL121077 | SN 49537 |
| ST023312 | ST24038173 | STL298442 |
| THIDIAZURON | TR-036946 | Thidiauron |
| Thidiazuran | Thidiazuron [ANSI:BSI:ISO] | Thidiazuron, PESTANAL(R), analytical standard |
| Thidiazuron, plant cell culture tested, BioReagent | Tox21_300651 | UNII-0091WH7STF |
| UREA,N-PHENYL-N'-1,3,4-THIADIAZOL-2-YL- | Urea, 1-phenyl-3-(1,2,3-thiadiazol-5-yl)- | Urea, N-phenyl-N'-1,2,3-thiadiazol-5-yl- |
| Urea, N-phenyl-N'-1,2,3-thiadiazol-5-yl- (9CI) | VA11865 | W-105872 |
| WA1; | ZINC73715 | ZX-AFC000685 |