D1134 | tributyltin benzoate
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 0.15±0.23 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 0.5 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 5.33±4.70 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Danger |
Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 1 of 40 companies. For more detailed information, please visit ECHA C&L website Of the 2 notification(s) provided by 39 of 40 companies with hazard statement code(s): H301+H311 (97.44%): Toxic if swallowed or in contact with skin [Danger Acute toxicity, oral acute toxicity, dermal] H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] H311 (100%): Toxic in contact with skin [Danger Acute toxicity, dermal] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P260, P264, P270, P273, P280, P301+P310, P302+P352, P305+P351+P338, P312, P314, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | oral | 132mg/kg (132mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 934, 1969. | |
| rat | LD50 | skin | 503mg/kg (503mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 934, 1969. | |
| mouse | LD50 | intravenous | 178mg/kg (178mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00090, | |
| mouse | LD50 | oral | 108mg/kg (108mg/kg) | Archiv fuer Toxikologie. Vol. 23, Pg. 283, 1968. | |
| 4342-36-3 | Benzoic acid, tributylstannyl ester | Benzoyloxytributylstannane |
| Biomet 11 | C-55984 | CAS-4342-36-3 |
| Caswell No. 867AA | DSSTox_CID_14981 | DSSTox_GSID_34981 |
| DSSTox_RID_79233 | DTXSID5034981 | EINECS 224-399-8 |
| EPA Pesticide Chemical Code 083106 | KS-0000265S | LS-146427 |
| NCGC00164179-01 | NCGC00164179-02 | NCGC00164179-03 |
| NCGC00257290-01 | NSC 221308 | NSC-221308 |
| NSC221308 | Q27275993; | Stannane, (benzoyloxy)tributyl- |
| Stannane, benzoyloxytributyl- | TRIBUTYLTIN BENZOATE | Tin, (benzoyloxy)tributyl- |
| Tin, (benzoyloxy)tributyl- (7CI) | Tin, benzoate | Tin, tributyl-, benzoate |
| Tox21_303395 | Tri-n-butyl-zinn benzoate | Tri-n-butyl-zinn benzoate [German] |
| Tri-n-butyltin benzoate | Tributylstannyl benzoate | Tributyltin benzoate, 98% |
| Tris(n-butyl)tin benzoate | WLN: 4-SN-4&4&OVR | ZINC170172514 |
| tri-n-butylbenzoyloxytin |
| CAS Number | 4342-36-3 |
| PubChem Compound | 16682834 |