D1143 | trifluralin
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 46.68±9.14 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 39.81 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 32.62±23.13 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
   |
Warning |
H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H351: Suspected of causing cancer [Warning Carcinogenicity] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P261, P272, P273, P280, P281, P302+P352, P308+P313, P321, P333+P313, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Danger |
Aggregated GHS information provided by 294 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (12.59%): Harmful if swallowed [Warning Acute toxicity, oral] H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin] H330 (12.59%): Fatal if inhaled [Danger Acute toxicity, inhalation] H351 (98.64%): Suspected of causing cancer [Warning Carcinogenicity] H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (99.66%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P281, P284, P301+P312, P302+P352, P304+P340, P308+P313, P310, P320, P321, P330, P333+P313, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H351: Suspected of causing cancer [Warning Carcinogenicity] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P261, P272, P273, P280, P281, P302+P352, P308+P313, P321, P333+P313, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H303: May be harmful if swallowed [Warning Acute toxicity, oral] H316: Causes mild skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] |
P261, P264, P272, P280, P302+P352, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P363, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P273, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rabbit | LD50 | oral | > 2gm/kg (2000mg/kg) | Pesticide Manual. Vol. 9, Pg. 851, 1991. | |
| rat | LD50 | skin | > 5gm/kg (5000mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. | |
| mouse | LD50 | intraperitoneal | 4600mg/kg (4600mg/kg) | Bulletin of Environmental Contamination and Toxicology. Vol. 20, Pg. 554, 1978. | |
| mouse | LD50 | oral | 3197mg/kg (3197mg/kg) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 16, Pg. 557, 1991. | |
| rat | LC50 | inhalation | 2800mg/m3/1H (2800mg/m3) | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 16, Pg. 557, 1991. | |
| chicken | LD50 | oral | > 2gm/kg (2000mg/kg) | Pesticide Manual. Vol. 9, Pg. 851, 1991. | |
| mammal (species unspecified) | LDLo | unreported | 5gm/kg (5000mg/kg) | "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 604, 1986. | |
| rat | LD50 | oral | 1930mg/kg (1930mg/kg) | Food and Chemical Toxicology. Vol. 30, Pg. 1031, 1992. | |
| dog | LD50 | oral | > 10gm/kg (10000mg/kg) | gastrointestinal: "hypermotility, diarrhea" | Food and Chemical Toxicology. Vol. 30, Pg. 1031, 1992. |
| mammal (species unspecified) | LD50 | oral | 3700mg/kg (3700mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1188, 1966. | |
| (2,6-Dinitro-4-trifluoromethyl-phenyl)-dipropyl-amine | .alpha.,.alpha.,.alpha.-Trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine | 1582-09-8 |
| 2,6-Dinitro-4-trifluormethyl-N,N-dipropylanilin | 2,6-Dinitro-4-trifluormethyl-N,N-dipropylanilin [German] | 2,6-Dinitro-6-trifluormethyl-N,N-dipropylanilin |
| 2,6-Dinitro-6-trifluormethyl-N,N-dipropylanilin [German] | 2,6-Dinitro-N,N-di-n-propyl-.alpha.,.alpha.,.alpha.-trifluoro-p-toluidine | 2,6-Dinitro-N,N-di-n-propyl-alpha,alpha,alpha-trifluoro-p-toluidine |
| 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)-benzamine | 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline | 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline # |
| 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine | 2,6-Dinitro-N,N-dipropyl-4-(trifluoromethyl)benzeneamine | 2,6-Dinitro-N,N-dipropyl-4-trifluoromethylaniline |
| 2,6-dinitro-N,N-dipropyl-4-(tri fluoromethyl)benzenamine | 2,6-dinitro-N,N-dipropyl-4-trifluoromethyl-aniline | 2,6-dinitro-N,N-dipropyl-alpha,alph a,alpha-trifluoro-p-toluidine |
| 2,6-dinitro-N,N-dipropyl-alpha,alpha,alpha-trifluoro-p-toluidine | 4-(Di-n-propylamino)-3,5-dinitro-1-(trifluoromethyl)benzene | 4-(Di-n-propylamino)-3,5-dinitro-1-trifluoromethylbenzene |
| 4-(Trifluoromethyl)-2,6-dinitro-N,N-dipropylaniline | 4-(di-n-propylamino)-3,5-dinitro-1-trifluoromethylbenzene | 4-DIPROPYLAMINO-3,5-DINITROBENZO-TRIFLUORIDE |
| 582T098 | 71281-30-6 | 75635-23-3 |
| A,A,A-TRIFLUORO-2,6-DINITRO-N,N-DIPROPYL-P-TOLUIDINE | A809905 | AI3-28203 |
| AKOS005608916 | Agreflan | Agriflan 24 |
| Agriphlan 24 | BIDD:ER0382 | BIDD:PXR0025 |
| BRN 1893555 | BSPBio_002359 | Benezeneamine, 2,6-di nitro-N,N-dipropyl-4-(trifluoromethyl)- |
| Benezeneamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)- | Benzenamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)- | Benzenamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)- (9CI) |
| Benzeneamine, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)- | Brassix | C14343 |
| C8BX46QL7K | CAS-1582-09-8 | CCG-39426 |
| CCRIS 607 | CHEBI:35027 | CHEMBL31970 |
| CS-5200 | CTK5E1805 | Caswell No. 889 |
| Commence | Crisalin | Crisalina |
| DB-043382 | DSSTox_CID_1395 | DSSTox_GSID_21395 |
| DSSTox_RID_76136 | DTXSID4021395 | Digermin |
| DivK1c_006536 | EBD43337 | EINECS 216-428-8 |
| EN300-67184 | EPA Pesticide Chemical Code 036101 | Elancolan |
| FT-0603564 | HSDB 1003 | HY-B2050 |
| I703 | Ipersan | J-009482 |
| K-4963 | KBio1_001480 | KBio2_002341 |
| KBio2_004909 | KBio2_007477 | KBio3_001859 |
| KBioGR_001079 | KBioSS_002344 | KF10033 |
| KS-5357 | L-36352 | LS-906 |
| Lilly 36,352 | MCULE-3549367398 | MLS002454453 |
| N,N-Di-n-propyl-2,6-dinitro-4-trifluoromethylaniline | N,N-Dipropyl-2,6-dinitro-4-trifluormethylanilin | N,N-Dipropyl-2,6-dinitro-4-trifluormethylanilin [German] |
| N,N-Dipropyl-2,6-dinitro-4-trifluoromethylaniline | N,N-Dipropyl-4-trifluoromethyl-2,6-dinitroaniline | N,N-di-n-propyl-2,6-dinitro-4-(trifluoromethyl)aniline |
| N,N-dipropyl-2,6-dini tro-4-trifluoromethylaniline | NCGC00091301-01 | NCGC00091301-02 |
| NCGC00091301-03 | NCGC00091301-04 | NCGC00091301-05 |
| NCGC00091301-06 | NCGC00091301-07 | NCGC00091301-08 |
| NCGC00254821-01 | NCGC00258904-01 | NCI C00443 |
| NCI-C00442 | Nitran | Nitran K |
| Olitref | PREMERLIN | Q418247 |
| SCHEMBL21994 | SMR000778097 | SPBio_001796 |
| SPECTRUM330038 | ST046418 | STK792949 |
| Scotts Stop Weeds Before They Start | Sinflouran | SpecPlus_000440 |
| Spectrum2_001888 | Spectrum3_000830 | Spectrum4_000670 |
| Spectrum5_001972 | Spectrum_001839 | Su seguro carpidor |
| Super-Treflan | Synfloran | TREFLAN(R) |
| TRIFLURALIN EC | Tox21_201352 | Tox21_300918 |
| Trefanocide | Treficon | Trefl an 10G |
| Treflam | Treflan | Treflan (trifluralin) |
| Treflan 10G | Treflan 4EC | Treflan 5G |
| Treflan EC | Treflan MTF | Treflan TR-10 |
| Treflanocide elancolan | Tri-4 | Trifloran |
| Trifluralin 10 microg/mL in Cyclohexane | Trifluralin 100 microg/mL in Methanol | Trifluralin [ANSI:BSI:ISO] |
| Trifluralin solution, 100 mug/mL in acetonitrile, PESTANAL(R), analytical standard | Trifluralin, PESTANAL(R), analytical standard | Trifluralin, analytical standard |
| Trifluralin, technical grade | Trifluralin2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline | Trifluralina 600 |
| Trifluraline | Trifluraline [ISO-French] | Triflurex |
| Trifurex | Trikepin | Trilin |
| Trilin 4EC | Trimaran (Salt/Mix) | Tristar |
| UNII-C8BX46QL7K | ZINC3873953 | ZSDSQXJSNMTJDA-UHFFFAOYSA-N |
| Zeltoxone | [2,6-dinitro-4-(trifluoromethyl)phenyl]dipropylamine | agrefla; |
| alpha,alpha,alpha-Trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine | alpha,alpha,alpha-trifluoro-2,6-dinitro-n,n-dipropyl-p-toluidine | elanocolan |
| p-Toluidine, .alpha.,.alpha.,.alpha.-trifluoro-2,6-dinitro-N,N-dipropyl- | p-Toluidine, alpha,alpha,alpha-trifluoro-2,6-dinitro-N,N-dipropyl- | trifluralin |
| trifluralin;2,6-dinitro-n,n-dipropyl-4-(trifluoromethyl)-benzamine | trifuraline |