Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
2-(4-hydroxy-1H-indol-3-yl)acetamide | 2-(4-hydroxyindol-3-yl)acetamide | 2-(4-oxidanyl-1H-indol-3-yl)ethanamide |
4-hydroxy-1H-Indole-3-acetamide | AKOS001586358 | BDBM49136 |
CBDivE_002318 | CHEMBL1522203 | Cambridge id 5106694 |
HMS2371J22 | MCULE-9143898485 | MLS000052983 |
Oprea1_492111 | SCHEMBL1395836 | SMR000068939 |
SR-01000388255 | SR-01000388255-1; | ST50894410 |
STK386805 | ZINC2464568 | cid_2053734 |
CAS Number | 103404-85-9 |
PubChem Compound | 2053734 |
BindingDB | 49136.0 |