Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
4-chloro-N-(2-hydroxyphenyl)benzenesulfonamide | AKOS002248584 | CBDivE_012094 |
MCULE-6583659788 | N-(2-hydroxyphenyl)-4-chlorobenzenesulfonamide | SCHEMBL3260803 |
ST50209835 | STK951108 | UTNJRYLWJOXNFX-UHFFFAOYSA-N |
ZINC288815 | [(4-chlorophenyl)sulfonyl](2-hydroxyphenyl)amine; |
PubChem Compound | 789223 |