Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
(3-bromo-4-hydroxyphenyl)[(4-chlorophenyl)sulfonyl]amine; | AB00074689-01 | AKOS002306612 |
BDBM50076489 | CHEMBL3416549 | Cambridge id 5158529 |
MCULE-8857982962 | SR-01000197316 | SR-01000197316-1 |
ST50774395 | ZINC762987 |
PubChem Compound | 1070505 |