Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
2-Chloro-6-methyl-indolo[1,2-c]quinazolin-12-ylamine | 2-chloro-6-methylindolo[1,2-c]quinazolin-12-amine | AKOS000558167 |
CBDivE_008819 | Cambridge id 5219795 | MCULE-9509284061 |
Oprea1_380698 | Oprea1_848312 | SR-01000454930 |
SR-01000454930-1; | STL328466 | ZINC235485 |
PubChem Compound | 762539 |