Compound
D1179 | 4-(2,3-Dihydro-1H-benzo[f]cyclopenta[c]quinolin-4-yl)benzene-1,2-diol
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
| 4-(1,2,3-trihydrobenzo[f]cyclopenta[2,1-c]quinolin-4-yl)benzene-1,2-diol; | 4-(2,3-dihydro-1H-benzo[f]cyclopenta[c]quinolin-4-yl)-1,2-benzenediol | 4-(2,3-dihydro-1H-benzo[f]cyclopenta[c]quinolin-4-yl)benzene-1,2-diol |
| AKOS001578195 | BDBM375043 | BDBM46291 |
| CHEMBL1560628 | HMS2533O17 | MCULE-6073126280 |
| MLS000595076 | Oprea1_231130 | SCHEMBL14907850 |
| SMR000184811 | ST50907207 | STK369748 |
| US10252984, Table 2.4 | ZINC13125138 | cid_5718744 |
| PubChem Compound | 781102 |