Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
8-Chloro-2,2-dimethyl-2,3-dihydro-1H,10H-phenothiazin-4-one; | 8-chloro-2,2-dimethyl-2,3-dihydro-1H-phenothiazin-4(10H)-one | AH-262/31834028 |
AKOS001642869 | CBDivE_009145 | CHEMBL1562756 |
Cambridge id 5219661 | HMS2801I09 | Kinome_3441 |
MCULE-2361032864 | MLS001030194 | Oprea1_797658 |
SMR000425567 | SR-01000484069 | SR-01000484069-1 |
STK837251 | ZINC786525 |
PubChem Compound | 741186 |