Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
2,5-Dihydroxy-3',4'-dimethyl[sulfonylbisbenzene] | 2-[(3,4-Dimethylphenyl)sulfonyl]-1,4-benzenediol | 2-[(3,4-dimethylphenyl)sulfonyl]benzene-1,4-diol; |
AB00075214-01 | CBDivE_005174 | CHEMBL1527937 |
Cambridge id 5210729 | HMS1609A05 | HMS2618M06 |
MCULE-4262267482 | MLS000685543 | Oprea1_836039 |
SMR000312507 |
PubChem Compound | 773181 |