Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
3-nitro-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]benzamide | AB00075184-01 | AKOS001428755 |
CBDivE_005019 | Cambridge id 5210298 | EU-0067947 |
MCULE-8481477097 | N-(5-isopropyl-1,3,4-thiadiazol-2-yl)-3-nitrobenzamide | N-[5-(methylethyl)(1,3,4-thiadiazol-2-yl)](3-nitrophenyl)carboxamide; |
Oprea1_660133 | SR-01000395112 | SR-01000395112-1 |
ST050336 | STK720064 | ZINC34695 |
PubChem Compound | 672835 |