Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
1H-Isoindole-1,3(2H)-dione, 2-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-; | 2-(2-(5-hydroxy-1H-indol-3-yl)ethyl)isoindole-1,3-dione | 2-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-1H-isoindole-1,3(2H)-dione |
2-[2-(5-hydroxyindol-3-yl)ethyl]benzo[c]azoline-1,3-dione | 5-Hydroxy-3-(2-phthalimidoethyl)-1H-indole | 53157-46-3 |
AB00073773-01 | AI-981/36563018 | AKOS000623773 |
CBDivE_000438 | CHEMBL1606430 | CTK1G1307 |
Cambridge id 5106791 | ChemDiv2_003209 | DTXSID60355048 |
EU-0000224 | HMS1378B19 | HMS2640H03 |
MCULE-5357903361 | MLS000703291 | Oprea1_158047 |
Oprea1_523437 | QXPSOWPOHSZKEK-UHFFFAOYSA-N | SCHEMBL2531516 |
SMR000273755 | SR-01000389832 | SR-01000389832-1 |
ST50888660 | STK028833 | ZINC290473 |
CAS Number | 53157-46-3 |
PubChem Compound | 790197 |