Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
(2Z)-2-(acetylamino)-N-(4-hydroxyphenyl)-3-phenylacrylamide | (2Z)-2-(acetylamino)-N-(4-hydroxyphenyl)-3-phenylprop-2-enamide | (Z)-2-(acetylamino)-N~1~-(4-hydroxyphenyl)-3-phenyl-2-propenamide; |
AB00074571-01 | AKOS000485325 | ARONIS018642 |
CHEMBL1872355 | HMS1554H10 | HMS2740I15 |
MLS000715224 | SMR000275203 | SR-01000507504 |
SR-01000507504-1 | ST095028 | STK041903 |
ZINC4526333 |
PubChem Compound | 5403184 |