Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
1-Methyl-2-(4-chloro-trans-styryl)-1H-benzoimidazole | 2-[(1E)-2-(4-chlorophenyl)vinyl]-1-methylbenzimidazole | 2-[(E)-2-(4-Chlorophenyl)ethenyl]-1-methyl-1H-benzimidazole |
2-[(E)-2-(4-Chlorophenyl)ethenyl]-1-methyl-1H-benzimidazole # | 259743-62-9; | AKOS002231935 |
CHEMBL226007 | Cambridge id 5663561 | N-Methyl-2-(4-chlorophenyl)eth-2-en-2-yl-1H-benzimidazole |
SCHEMBL8548385 | ST50116200 | STL257585 |
YUIBZEGEDQMBFQ-DHZHZOJOSA-N | ZINC3877123 |
CAS Number | 259743-62-9 |
PubChem Compound | 5377781 |