Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
S,N-GLYCEROPHOSPHATE SHUTTLE | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | affect | 162 | ||
Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
Glycerol-3-phosphate dehydrogenase, mitochondrial | ∼2.5 µM | rat | skeletal muscle mitochondria | measurement of superoxide/H2O2 production | inhibitor | 162 | ||
AB00075795-01 | AKOS000638306 | BRD-K20763024-001-01-4; |
CBDivE_010893 | CBKinase1_000108 | CBKinase1_012508 |
MCULE-3279385485 | Oprea1_010280 | Oprea1_575000 |
SCHEMBL15702608 | ZINC2473187 |
PubChem Compound | 2054851 |